ID D2V062_NAEGR Unreviewed; 1769 AA.
AC D2V062;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC49473.1};
GN ORFNames=NAEGRDRAFT_62183 {ECO:0000313|EMBL:EFC49473.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC49473.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC49473.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; GG738847; EFC49473.1; -; Genomic_DNA.
DR RefSeq; XP_002682217.1; XM_002682171.1.
DR STRING; 5762.D2V062; -.
DR EnsemblProtists; EFC49473; EFC49473; NAEGRDRAFT_62183.
DR GeneID; 8855279; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_62183; -.
DR eggNOG; KOG1217; Eukaryota.
DR eggNOG; KOG1225; Eukaryota.
DR InParanoid; D2V062; -.
DR OMA; HHGTCQN; -.
DR OrthoDB; 5471657at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 15.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR013111; EGF_extracell.
DR PANTHER; PTHR11219; TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR PANTHER; PTHR11219:SF69; TENEURIN-M; 1.
DR Pfam; PF07974; EGF_2; 1.
DR SMART; SM00181; EGF; 28.
DR PROSITE; PS00022; EGF_1; 16.
DR PROSITE; PS01186; EGF_2; 15.
DR PROSITE; PS50026; EGF_3; 12.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Reference proteome {ECO:0000313|Proteomes:UP000006671}.
FT DOMAIN 152..185
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 302..341
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 347..381
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 387..420
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 498..537
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 543..576
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 582..615
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 621..654
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 693..732
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 772..811
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 896..928
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1111..1150
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 175..184
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 331..340
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 371..380
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 410..419
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 527..536
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 566..575
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 605..614
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 644..653
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 722..731
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 801..810
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 918..927
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1140..1149
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1769 AA; 192523 MW; 0A3A29C9E95B4981 CRC64;
MNNTCSENGI CQDYNHCNCS SGFTSSNCSI PICFGSNATD ETVCSSHGQC LSPNNCSCSD
GYMHSDCSHP ICFGLESTNR NSCSTHGTCI SPNSCQCDGN HVGDMCEIPL CFNIPANHNS
TCSSSGKCIG VNLCECYGNF TGMNCSVPIC FDENSTSIMS CSSRGRCIGP NLCECQVGYT
GSVCEYPVCY GFYSEDVNSC SGHGECIDYN KCQCENGYVT ENCSIPVCFG LNSSDSNVCA
SHGDCLSPNN CSCHEGFTSI NCSISICYNS PATDPFACNG KGNCVNPNEC ACQEGNIGLQ
CEIPLCFGVP SNETQSCSGN GECIQYNECM CHSNFTGLNC SIPICFGINA TDQSHVCFSH
GICQEPDQCQ CHEGYTGIQC EIPICFNIPA TNSSTCASNG VCIDFNNCSC LDGYTSENCS
LPICYELDSG KSMVCSSHGQ CLAPNNCTCL ERFTFDNCSI PICYNIDASN SSVCSGFGEC
SSPNNCKCHE NHIGLQCEIP LCFGIPSNET QSCNGNGQCI QYNECVCNSD YTGIDCSIPI
CFGSNATNLT VCSSHGICQS PDQCQCQEGY TGTNCEIPIC FNIPANDSST CSSNGECIDF
NNCSCHDGYT SENCSIPICF NLNSTDSSVC NSNGICTSPD KCQCQENFTG ENCSIPICFG
LAANSSGACS ASGSCVYPNT CLCNQGIIGI NCEIPSCFGI FQNNSQSCSG NGICIELNKC
SCYLNFTGES CLISACNGIA SNDSSVCSGK GKCTAPNLCE SCEENYFGEW CEISQCFGIF
SNQSQVCSEN GKCESYNNCN CSMGYVGENC NIPVCFKINS TDENVCNSNG ICTSPDLCSC
NSKYGGLECS EPKCFGKTTL EGACSSKGNC TQPDSCTCEK GFFGISCELH SCFGIQLNDS
SVICSGHGEC KSLDECECDS GYLGESCSIH TCFGITFNES GVCSGNGSCS SLDNCTCYGD
GKFYANCTLI PSDSPIIDSD VPSNHTEISN NSSSYPNCFN ISANHSNVCN GNGNCTSENE
CKCREGYFGG ECSLFACFGK ESADSSVCSS NGICASPNTC KCRPERYGSQ CQLVKCFEIL
SNQSNVCSSK GSCQDTNACI CNEGYFGPMC NITSCEGILS NNSQVCNGSG QCTHYNTCQC
KEGFIGLNCQ FTKCNSTSCR HGSCITTSQC ECESGWTSSE CNLPICYDLL ASDSNVCSTH
GKCIAPNKCN CSTNPLYMGD KCQYLQLDSL QCSINPSLNL IPIEWTISGL DKITFDMSSK
EILVRNSIPY STSLHSKSKF NYELNIYNTG KRSFNYQINS FCENGISFKQ LGISSQFGLL
QEGNNANIKD LQNIGFALFW NDESLKYEDI KCHVELIVNP KDQFDECQHY DSNTETSSKY
NITLILERTN VCQFLKETDL PLTFSSTQLS TMSEIALIDE NILSDNDILK IINTFTQKRN
NWQIINKDNS TLQANILLTA QLSNPNNELG LFVPSLICKD ERIVDDIEFT TEYLSNQSPF
SISHSLQKIQ FQFNVTIKNV SNYVDYGRVR GGKEGMATVL IEDMLLNCSL ILLPNPSECW
SNTNRNSTFS KYIISHFTLP IVSGEFSFFQ AVRSFEIGII TLTYTCMGIG FASMICTTKV
PRDRKHSLLQ LVEFVKEKRR NKLNSTSDDS KPLLENQIDR PYCENCGHHT RKKARYAIRV
ENYDANCEMF ICENQVCFEA MISLHNRGYS HHYQCFDLDK EEDCQLMIET PFKTLADNFD
ESDIYESMDI EFPIPSDIND DEEDDSDLF
//
