ID D2VGS2_NAEGR Unreviewed; 410 AA.
AC D2VGS2;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC44017.1};
GN ORFNames=NAEGRDRAFT_49407 {ECO:0000313|EMBL:EFC44017.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC44017.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC44017.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
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DR EMBL; GG738870; EFC44017.1; -; Genomic_DNA.
DR RefSeq; XP_002676761.1; XM_002676715.1.
DR AlphaFoldDB; D2VGS2; -.
DR EnsemblProtists; EFC44017; EFC44017; NAEGRDRAFT_49407.
DR GeneID; 8848032; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_49407; -.
DR eggNOG; KOG3019; Eukaryota.
DR InParanoid; D2VGS2; -.
DR OrthoDB; 5486782at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013549; DUF1731.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR11092:SF0; EPIMERASE FAMILY PROTEIN SDR39U1; 1.
DR PANTHER; PTHR11092; SUGAR NUCLEOTIDE EPIMERASE RELATED; 1.
DR Pfam; PF08338; DUF1731; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006671}.
FT DOMAIN 54..323
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
FT DOMAIN 360..405
FT /note="DUF1731"
FT /evidence="ECO:0000259|Pfam:PF08338"
SQ SEQUENCE 410 AA; 45976 MW; 7CC9B8FFB22587C5 CRC64;
MIKSIKQQHS MAKFMMKTTA NQNVMIFHQA KQQGFHQNVK LANNQNAQLS HLVIGGGSGF
LGKQVLKQLL KSHKGAAGDG FTQFQDELSN LSQITIISRN PKETKLALEK ELKNLNLEKN
SLIQIGVKNW KDDDSVFLFN HQIFDEKETY GRDKKVAAIN LSGVSIGKQS WTPKYRKEIF
ESRTKTTLDL IQYLDSFGES ASTFIGTSAV GFYPCTTDGN QTNVYTEDLT TPANNQFGEL
TNAVEEAIKN TNSNNIKNKI IMRPGVLIGK GGGVLNDMMV PYIGLAIPIV FGNGNQPFSC
IHLEDAANMY IHALYQNFNS QNKQVAIYNT VMPELVNFKQ FVKCLNSKAN PFSFPLIPFP
YSIVKTIFGK ERAQLLCEGQ FVLPARAQQE NFQFKYPTLD SMIEQVTSRK
//
