ID D2VH03_NAEGR Unreviewed; 178 AA.
AC D2VH03;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=ARF/SAR family small GTPase {ECO:0000313|EMBL:EFC43898.1};
GN ORFNames=NAEGRDRAFT_56408 {ECO:0000313|EMBL:EFC36042.1},
GN NAEGRDRAFT_77418 {ECO:0000313|EMBL:EFC43898.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC43898.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC43898.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Arf family.
CC {ECO:0000256|RuleBase:RU003925}.
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DR EMBL; GG738953; EFC36042.1; -; Genomic_DNA.
DR EMBL; GG738871; EFC43898.1; -; Genomic_DNA.
DR RefSeq; XP_002668786.1; XM_002668740.1.
DR RefSeq; XP_002676642.1; XM_002676596.1.
DR STRING; 5762.D2VH03; -.
DR EnsemblProtists; EFC36042; EFC36042; NAEGRDRAFT_56408.
DR EnsemblProtists; EFC43898; EFC43898; NAEGRDRAFT_77418.
DR GeneID; 8850067; -.
DR GeneID; 8856339; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_56408; -.
DR eggNOG; KOG0070; Eukaryota.
DR OMA; VSETMEM; -.
DR OrthoDB; 5473252at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd00878; Arf_Arl; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR11711; ADP RIBOSYLATION FACTOR-RELATED; 1.
DR PANTHER; PTHR11711:SF31; ADP-RIBOSYLATION FACTOR-LIKE 5; 1.
DR Pfam; PF00025; Arf; 1.
DR PRINTS; PR00328; SAR1GTPBP.
DR SMART; SM00177; ARF; 1.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00178; SAR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51417; ARF; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU003925};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003925};
KW Reference proteome {ECO:0000313|Proteomes:UP000006671}.
SQ SEQUENCE 178 AA; 20216 MW; 2E6334E19CA59667 CRC64;
MGQLLSNMIK GLSLFEQKEA KILFLGLDAA GKTSTLYKIQ LDENVSTIPT IGFNAEVIQY
KRVQFRVFDI GGQDMIRTLW RHYYNGTDAV IFIVDSNDRE RFEEVSETLH KVMEDPSLSN
AKLLVWANKQ DLPRAANVTD IAKNLQLNSI KQDWYIQPCS ALNGSGLFEG LDWLSNKL
//
