ID D2VM59_NAEGR Unreviewed; 223 AA.
AC D2VM59;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Mammalian ependymin-related protein 1 {ECO:0000256|ARBA:ARBA00020678};
GN ORFNames=NAEGRDRAFT_70020 {ECO:0000313|EMBL:EFC42264.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC42264.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC42264.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
CC -!- FUNCTION: Binds anionic lipids and gangliosides at acidic pH.
CC {ECO:0000256|ARBA:ARBA00002024}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
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DR EMBL; GG738881; EFC42264.1; -; Genomic_DNA.
DR RefSeq; XP_002675008.1; XM_002674962.1.
DR AlphaFoldDB; D2VM59; -.
DR EnsemblProtists; EFC42264; EFC42264; NAEGRDRAFT_70020.
DR GeneID; 8851817; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_70020; -.
DR InParanoid; D2VM59; -.
DR OrthoDB; 5473774at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
DR InterPro; IPR001299; Ependymin.
DR PANTHER; PTHR10697; MAMMALIAN EPENDYMIN-RELATED PROTEIN 1; 1.
DR PANTHER; PTHR10697:SF1; MAMMALIAN EPENDYMIN-RELATED PROTEIN 1; 1.
DR Pfam; PF00811; Ependymin; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006671};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..223
FT /note="Mammalian ependymin-related protein 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003038590"
SQ SEQUENCE 223 AA; 24685 MW; E8F9FAEC5797D608 CRC64;
MIKIVTALFA LACLIVFASA QTQHCFDKSF QTRVRVFEPK RDFFDTQTMY VDADAGLTRI
DMLVREPVSR NVSVYLNYNT MKSYTYDIVT GTCNVIVLSQ PQQPFCISSN ATYARSDVLG
GTLKVDVYEE KVFGFQAKIS YAPNTNIPVS VITKAAGVGS GYVIEEFFNW IHQKPASAVF
TLPAACQRLS GPSMRMANSD SAIIGRVQSL LFRNAIKKAS AKL
//
