ID   D2YCF9_VIBMI            Unreviewed;       918 AA.
AC   D2YCF9;
DT   02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   02-MAR-2010, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=Protease {ECO:0000313|EMBL:EEW07581.1};
GN   ORFNames=VMB_12060 {ECO:0000313|EMBL:EEW07581.1};
OS   Vibrio mimicus VM603.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=671074 {ECO:0000313|EMBL:EEW07581.1, ECO:0000313|Proteomes:UP000004827};
RN   [1] {ECO:0000313|EMBL:EEW07581.1, ECO:0000313|Proteomes:UP000004827}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VM603 {ECO:0000313|EMBL:EEW07581.1,
RC   ECO:0000313|Proteomes:UP000004827};
RX   PubMed=19860885; DOI=10.1186/1471-2148-9-258;
RA   Thompson C.C., Vicente A.C., Souza R.C., Vasconcelos A.T., Vesth T.,
RA   Alves N.Jr., Ussery D.W., Iida T., Thompson F.L.;
RT   "Genomic taxonomy of Vibrios.";
RL   BMC Evol. Biol. 9:258-258(2009).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEW07581.1}.
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DR   EMBL; ACYU01000041; EEW07581.1; -; Genomic_DNA.
DR   RefSeq; WP_000848973.1; NZ_ACYU01000041.1.
DR   AlphaFoldDB; D2YCF9; -.
DR   MEROPS; M06.002; -.
DR   Proteomes; UP000004827; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd00146; PKD; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR048665; InhA-like_VEG.
DR   InterPro; IPR012300; Pept_M6_InhA.
DR   InterPro; IPR008757; Peptidase_M6-like_domain.
DR   InterPro; IPR022409; PKD/Chitinase_dom.
DR   InterPro; IPR000601; PKD_dom.
DR   InterPro; IPR035986; PKD_dom_sf.
DR   NCBIfam; TIGR03296; M6dom_TIGR03296; 1.
DR   PANTHER; PTHR13062; COLLAGENASE; 1.
DR   PANTHER; PTHR13062:SF12; PRE-PRO-METALLOPROTEASE PRTV; 1.
DR   Pfam; PF20773; InhA-like_MAM; 1.
DR   Pfam; PF20774; InhA-like_VEG; 1.
DR   Pfam; PF05547; Peptidase_M6; 1.
DR   Pfam; PF00801; PKD; 1.
DR   Pfam; PF18911; PKD_4; 1.
DR   PIRSF; PIRSF007519; Protease_InhA; 1.
DR   SMART; SM00089; PKD; 2.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
DR   SUPFAM; SSF49299; PKD domain; 2.
DR   PROSITE; PS50093; PKD; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:EEW07581.1};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..918
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003039000"
FT   DOMAIN          758..836
FT                   /note="PKD"
FT                   /evidence="ECO:0000259|PROSITE:PS50093"
SQ   SEQUENCE   918 AA;  101624 MW;  19E12A054356FFB9 CRC64;
     MKTIKKTLLA TAVATFFSSG LYAQTPIDLG VVNEDKLIEM LVRTGQISAD ASDSDKRIAL
     ERYLDEKIRS GFKGDAQFGK KALEQRAKIL KVIDKQKGPH KARVFALDVG QKRTDKVLAL
     LIDFPDLPWD DNRLTKEHTE MLYDRYEPSH YQDLLFSDKG YTGPNGENFI SMRQYYESES
     GNSYSVSGQA AGWYRASKNA SYYGGNSPTT NSDLHAQELV REALDQLARD PSINLADYDI
     EDRYDYNGNG NFREPDGVID HLMIFHASVG EEAGGGVLGK DAIWSHRFNL GRYHVLEGTQ
     SQVPGRFGGQ YAAFDYTIQP IDAAAGVCAH EYGHDLGLPD EYDTQYTGAG EPVSYWSIMS
     SGSWAGKIGG TQPTAFSSWA KQFLQNSIGG RWINHEQLSI NELEAKPRVM TLFQTTDNAR
     PNMVKVTLPI KRVDGIKPAE GEFSFYSNRG DDLRNRMSRQ LAIPAGSNAT LHFKAWFQIE
     KDYDFARVLI NGQQIAGSIT TMDDPYNTGL APAISGDSAG WIDAQFDLSA WAGQTVELAF
     DYVTDGGLAM EGLYVDDLRL DVDGNESLID NAEGESSFAF NGFTKNGGFH EANHYYLLQW
     RSHNDVDQGL ANLKRFGQLM SFEPGLLVWY VDESYADNWV GKHPGEGWLG VVDADQNALV
     WSKTGEVAQT RFQVRDAAFS LFDQAPLKLA TTDGNTLEDM NLTANASFSD DQDYSSPQAP
     DSGRKVMPFG LKIDLLSQSK ENEYGVVRLS KVTTENIAPV ARFELKVEGL SVTSQNTSSD
     SDGSITSYLW DFGNGQTSTE AAPTWSYANA GSYQVTLTVT DDKGATDTHQ QTIKVEKPNA
     LPEASASYIH LGRWVTMWST STDSDGRIVD TEWTLPNGKI KRGRMFSSIF PSYGEHDVVL
     KVMDDRGAVT TKTIKVKL
//