ID D2ZUI6_NEIMU Unreviewed; 290 AA.
AC D2ZUI6;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:EFC89372.1};
DE EC=1.3.1.12 {ECO:0000313|EMBL:EFC89372.1};
GN ORFNames=NEIMUCOT_04275 {ECO:0000313|EMBL:EFC89372.1};
OS Neisseria mucosa ATCC 25996.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=546266 {ECO:0000313|EMBL:EFC89372.1, ECO:0000313|Proteomes:UP000003344};
RN [1] {ECO:0000313|EMBL:EFC89372.1, ECO:0000313|Proteomes:UP000003344}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25996 {ECO:0000313|EMBL:EFC89372.1,
RC ECO:0000313|Proteomes:UP000003344};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFC89372.1}.
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DR EMBL; ACDX02000003; EFC89372.1; -; Genomic_DNA.
DR RefSeq; WP_003741690.1; NZ_ACDX02000003.1.
DR AlphaFoldDB; D2ZUI6; -.
DR STRING; 546266.NEIMUCOT_04275; -.
DR GeneID; 61322880; -.
DR eggNOG; COG0287; Bacteria.
DR Proteomes; UP000003344; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EFC89372.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003344}.
FT DOMAIN 5..290
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 290 AA; 32023 MW; 3D4D0F503E25B192 CRC64;
MNTLKHIVLI GVGLIGGSFV LDLKRLGLVD TVTGIDLDRD NLDRALERRV IDRAYTQIDA
LSMHEADLAV IATPVSTFPD ICRAVRPYLN AHTVVTDVGS TKQSAVQAFC SVLPEHLSRC
IAAHPIAGSD RSGALSAQFG LFQDRKLVIT PHGEENEQAA GLVENLWRAV GAQTFRMSAE
EHDAVFAAVS HMPHLAAFAY VHQIADHPDG RHYLEFAATG FRDFTRIASS HPAVWTDICL
ANKNSLLDLI GGLRTQLSEL ERILSEEDRA ALYRYFAAAK QTRDEWLERQ
//
