ID D2ZUP0_NEIMU Unreviewed; 598 AA.
AC D2ZUP0;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Creatinase {ECO:0000313|EMBL:EFC89046.1};
GN ORFNames=NEIMUCOT_04330 {ECO:0000313|EMBL:EFC89046.1};
OS Neisseria mucosa ATCC 25996.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=546266 {ECO:0000313|EMBL:EFC89046.1, ECO:0000313|Proteomes:UP000003344};
RN [1] {ECO:0000313|EMBL:EFC89046.1, ECO:0000313|Proteomes:UP000003344}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25996 {ECO:0000313|EMBL:EFC89046.1,
RC ECO:0000313|Proteomes:UP000003344};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFC89046.1}.
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DR EMBL; ACDX02000004; EFC89046.1; -; Genomic_DNA.
DR RefSeq; WP_003741767.1; NZ_ACDX02000004.1.
DR AlphaFoldDB; D2ZUP0; -.
DR STRING; 546266.NEIMUCOT_04330; -.
DR GeneID; 61323985; -.
DR eggNOG; COG0006; Bacteria.
DR Proteomes; UP000003344; Unassembled WGS sequence.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000003344}.
FT DOMAIN 9..129
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 307..520
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 537..596
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 598 AA; 64885 MW; 25CFC38086A28E14 CRC64;
MNTVSNYLSA LREAMKAQGL DALVIPSADP HLSEYLPAHW QARRELSGFT GSVGTFVVTA
DEAGVWVDSR YWEQATKQLA GSGIELQKSG QVPPYNEWLA ANLSENAAVG IPSDMVSLTG
KRTLAQSLAA KNIRIEHPDD LLDRVWSSRP SIPAETVFIH DPAYVSETAA EKLARVRAVM
AEKGADYHLV SSLDDIAWLT NLRGSDVPFN PVFVSFLLIG KDNAVLFTDQ GRLNAEAAAA
LQTAGITVEP YAQVADKLAQ IGGALLIEPN KTAVSTLVRL PESVRLIEGI NPSTFFKSVK
SEADIVHIRE AMEHDGAALC GFFAEFEDII DNGGSLTEID VDTMLHRHRS ARPGFISLSF
DTIAGFNANA ALPHYSATPE SHSTISGNGL LLIDSGAQYK GGTTDITRVV PVGTPTAEQK
RDNTLVLKAH IALAEAVFPE NILSPMIDAI CRKPLWQAQC DYGHGTGHGV GYFLNVHEGP
QVIACAAVPG PQHAMKKGMV TSIEPGLYRP GKWGIRIENL AANQAVANPQ ETEFGSFLYF
ETLTLCPIDT RLMDTAMMTA GEIDWVNRYH AEVRRRLEPL TEGAAKAWLI KRTEPLAR
//
