ID D3DKG5_HYDTT Unreviewed; 332 AA.
AC D3DKG5;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Radical SAM domain protein {ECO:0000313|EMBL:BAI70317.1};
GN OrderedLocusNames=HTH_1873 {ECO:0000313|EMBL:BAI70317.1};
OS Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6).
OC Bacteria; Aquificota; Aquificae; Aquificales; Aquificaceae;
OC Hydrogenobacter.
OX NCBI_TaxID=608538 {ECO:0000313|EMBL:BAI70317.1, ECO:0000313|Proteomes:UP000002574};
RN [1] {ECO:0000313|EMBL:BAI70317.1, ECO:0000313|Proteomes:UP000002574}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6534 / IAM 12695 / TK-6 [Tokyo]
RC {ECO:0000313|Proteomes:UP000002574};
RX PubMed=20348262; DOI=10.1128/JB.00158-10;
RA Arai H., Kanbe H., Ishii M., Igarashi Y.;
RT "Complete genome sequence of the thermophilic, obligately
RT chemolithoautotrophic hydrogen-oxidizing bacterium Hydrogenobacter
RT thermophilus TK-6.";
RL J. Bacteriol. 192:2651-2652(2010).
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DR EMBL; AP011112; BAI70317.1; -; Genomic_DNA.
DR RefSeq; WP_012964497.1; NC_017161.1.
DR AlphaFoldDB; D3DKG5; -.
DR STRING; 608538.HTH_1873; -.
DR KEGG; hth:HTH_1873; -.
DR PATRIC; fig|608538.5.peg.1887; -.
DR eggNOG; COG1856; Bacteria.
DR OrthoDB; 5420460at2; -.
DR Proteomes; UP000002574; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR007197; rSAM.
DR PANTHER; PTHR43288; BIOTIN SYNTHASE-RELATED PROTEIN, RADICAL SAM SUPERFAMILY; 1.
DR PANTHER; PTHR43288:SF2; RADICAL SAM CORE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01113; Uncharacterised_Radical_SAM_Su; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002574};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 53..278
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 332 AA; 36840 MW; FFB2207FDAC3D374 CRC64;
MRIEEHLEGV ALDSTLLDKL YDGFRIRQQN FGNTIYFHSP GFKHYQVDDF KVSSAPKFVD
VSITGRHCEL MCDHCASKIL WHMIPATSPE ELIRVGQELK AKGIEGILIS GGSNKDGVVE
LNPFLKAMRY LKEELGMLVT CHVGLVDREL AEGLREAGVD AVLLDIIGDD RTIAEVYKMP
HKSVKDYEMS LKNLKDFGHS IVPHVIIGLH YGKILGEYRA IDMVSDFEPS ALVLVVVMPY
YGKAKFQLLP PPKAEESAMV ILHARKKLPS THVVIGCARP AGEERVKLDI YALHAGVNGI
TFPAEGVFSY AKSMGLEPVV SQNCCSTVFM PQ
//
