ID D3DMG7_DROME Unreviewed; 784 AA.
AC D3DMG7;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};
GN Name=CG1513-RA {ECO:0000313|EMBL:ADA53575.1};
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227 {ECO:0000313|EMBL:ADA53575.1};
RN [1] {ECO:0000313|EMBL:ADA53575.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Berkeley {ECO:0000313|EMBL:ADA53575.1};
RA Carlson J., Booth B., Frise E., Park S., Wan K., Yu C., Celniker S.;
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the OSBP family.
CC {ECO:0000256|RuleBase:RU003844}.
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DR EMBL; BT120036; ADA53575.1; -; mRNA.
DR AlphaFoldDB; D3DMG7; -.
DR VEuPathDB; VectorBase:FBgn0033463; -.
DR HOGENOM; CLU_012334_3_0_1; -.
DR ExpressionAtlas; D3DMG7; baseline and differential.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR CDD; cd13290; PH_ORP9; 1.
DR Gene3D; 1.10.287.2720; -; 1.
DR Gene3D; 2.40.160.120; -; 1.
DR Gene3D; 6.10.140.1150; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR037239; OSBP_sf.
DR InterPro; IPR000648; Oxysterol-bd.
DR InterPro; IPR018494; Oxysterol-bd_CS.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR10972; OXYSTEROL-BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR10972:SF102; OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 9; 1.
DR Pfam; PF01237; Oxysterol_BP; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF144000; Oxysterol-binding protein-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS01013; OSBP; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 2: Evidence at transcript level;
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055,
KW ECO:0000256|RuleBase:RU003845};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003845}.
FT DOMAIN 21..118
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 784 AA; 87384 MW; 1E3E06CA2C282814 CRC64;
MASTTGSAPS LGPPQSGSGG SGTLEGTLSK WTNVMKGWQY RFFVLDENAG LLSYYTSKDK
MIKGVRRGCV RLKDALIGID DQEDNTFTIT VDHKTFHFQA RHNEEREQWV RRLEDTIRRH
ANRSRLWDSQ SAFYIAGGYT KEGGGSGTGG RRPNHLELVA RRVSEADAYL QLMIEQTNLL
DKRIAELTDP AEQSKCKALQ DNANAMLDHI KHSIVSLQIA KNMAHPINGI YNGPPATAST
SSSTSGVAMG SCNNVQAGGL KVPLEGQVIG KGELVDDEED SATENATTAP LGLIVPATSY
SSSEGEEDFY DAYDDPFTSI GSSPIGCATR GFAETTSPTH EKAPDGFANA EPVAVGDSVA
PQTLPEIDES VADADTSIKT ARTAVSSRSA SYDNGIDYDA LYEEEEETDL SMEAHGSMIT
HLLSQVKIGM DLTKVVLPTF ILERRSLLEM YADYFAHPDL FIKISDLDDP RDRIVQVCRW
YMSAYHAGRK SAVAKKPYNP ILGEVFQCHW DIPGISQDAQ EVRDGPVPWC RRDQLTFLAE
QVSHHPPISA FYAEHYNKKI TFAAHVWTKS KFLGLSIGVH NIGEGVVTLV DRSEEYIVTF
PNGYGRSILT VPWIELGGSV EIKCPQSGYY ANVEFLTKPF YGGKRNRVSA EVYAPSEKKP
FVSITGEWSG LMEAKWHGKN KTEVFVDVNR IPIFKKQVRP IVEQDEYESR RVWKEVTAGL
KFNDIERATT AKFVVEQQQR DQAKVRKEYD LAWEHKHFKP VGDNWIYAKP LSQRMYLQEK
EAKR
//
