ID D3GUF3_ECO44 Unreviewed; 310 AA.
AC D3GUF3;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=LysR-family transcriptional regulator {ECO:0000313|EMBL:CBG34655.1};
GN OrderedLocusNames=EC042_1828 {ECO:0000313|EMBL:CBG34655.1};
OS Escherichia coli O44:H18 (strain 042 / EAEC).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=216592 {ECO:0000313|EMBL:CBG34655.1, ECO:0000313|Proteomes:UP000001407};
RN [1] {ECO:0000313|EMBL:CBG34655.1, ECO:0000313|Proteomes:UP000001407}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=042 / EAEC {ECO:0000313|Proteomes:UP000001407};
RX PubMed=20098708; DOI=10.1371/journal.pone.0008801;
RA Chaudhuri R.R., Sebaihia M., Hobman J.L., Webber M.A., Leyton D.L.,
RA Goldberg M.D., Cunningham A.F., Scott-Tucker A., Ferguson P.R.,
RA Thomas C.M., Frankel G., Tang C.M., Dudley E.G., Roberts I.S., Rasko D.A.,
RA Pallen M.J., Parkhill J., Nataro J.P., Thomson N.R., Henderson I.R.;
RT "Complete genome sequence and comparative metabolic profiling of the
RT prototypical enteroaggregative Escherichia coli strain 042.";
RL PLoS ONE 5:E8801-E8801(2010).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; FN554766; CBG34655.1; -; Genomic_DNA.
DR RefSeq; WP_000269493.1; NC_017626.1.
DR AlphaFoldDB; D3GUF3; -.
DR SMR; D3GUF3; -.
DR KEGG; elo:EC042_1828; -.
DR PATRIC; fig|216592.3.peg.1901; -.
DR HOGENOM; CLU_039613_35_1_6; -.
DR Proteomes; UP000001407; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30126; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR30126:SF18; LYSR FAMILY TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 2..59
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 310 AA; 35264 MW; AF6C42E908B794A0 CRC64;
MWSEYSLEVV DAVARNGSFS AAAQELHRVP SAVSYTVRQL EEWLAVPLFE RRHRDVELTA
AGAWFLKEGR SVVKKMQITR QQCQQIANGW RGQLAIAVDN IVRPERTRQM IVDFYRHFDD
VELLVFQEVF NGVWDALSDG RVELAIGATR AIPVGGRYAF RDMGMLSWSC VVASHHPLAL
MDGPFSDDTL RNWPSLVRED TSRTLPKRIT WLLDNQKRLV VPDWESSATC ISAGLCIGMV
PTHFAKPWLN EGKWVALELE NPFPDSACCL TWQQNDMSPA LTWLLEYLGD SETLNKEWLR
EPEETPATGD
//
