ID D3H1G9_ECO44 Unreviewed; 297 AA.
AC D3H1G9;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CBG35377.1};
GN OrderedLocusNames=EC042_2545 {ECO:0000313|EMBL:CBG35377.1};
OS Escherichia coli O44:H18 (strain 042 / EAEC).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=216592 {ECO:0000313|EMBL:CBG35377.1, ECO:0000313|Proteomes:UP000001407};
RN [1] {ECO:0000313|EMBL:CBG35377.1, ECO:0000313|Proteomes:UP000001407}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=042 / EAEC {ECO:0000313|Proteomes:UP000001407};
RX PubMed=20098708; DOI=10.1371/journal.pone.0008801;
RA Chaudhuri R.R., Sebaihia M., Hobman J.L., Webber M.A., Leyton D.L.,
RA Goldberg M.D., Cunningham A.F., Scott-Tucker A., Ferguson P.R.,
RA Thomas C.M., Frankel G., Tang C.M., Dudley E.G., Roberts I.S., Rasko D.A.,
RA Pallen M.J., Parkhill J., Nataro J.P., Thomson N.R., Henderson I.R.;
RT "Complete genome sequence and comparative metabolic profiling of the
RT prototypical enteroaggregative Escherichia coli strain 042.";
RL PLoS ONE 5:E8801-E8801(2010).
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. SDR39U1 subfamily. {ECO:0000256|ARBA:ARBA00009353}.
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DR EMBL; FN554766; CBG35377.1; -; Genomic_DNA.
DR RefSeq; WP_001028317.1; NC_017626.1.
DR AlphaFoldDB; D3H1G9; -.
DR KEGG; elo:EC042_2545; -.
DR PATRIC; fig|216592.3.peg.2662; -.
DR HOGENOM; CLU_047373_0_3_6; -.
DR Proteomes; UP000001407; Chromosome.
DR CDD; cd05242; SDR_a8; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013549; DUF1731.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR010099; SDR39U1.
DR NCBIfam; TIGR01777; yfcH; 1.
DR PANTHER; PTHR11092:SF0; EPIMERASE FAMILY PROTEIN SDR39U1; 1.
DR PANTHER; PTHR11092; SUGAR NUCLEOTIDE EPIMERASE RELATED; 1.
DR Pfam; PF08338; DUF1731; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
FT DOMAIN 3..215
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
FT DOMAIN 249..295
FT /note="DUF1731"
FT /evidence="ECO:0000259|Pfam:PF08338"
SQ SEQUENCE 297 AA; 32712 MW; 2345C83629A1DD47 CRC64;
MNIVITGGTG LIGRHLIPRL LELGHQITVM TRNPQKASSV LGPRVTLWQG LADQSNLNGV
DAVINLAGEP IADKRWTHEQ KERLCQSRWN ITQKLVDLIN ASDTPPSVLI SGSATGYYGD
LGEVVVTEEE PPHNEFTHKL CAHWEEIACR AQSDKTRVCL LRTGVVLAPD GGILGKMLPP
FRLGLGGPIG SGRQYLAWIH IDDMVNGILW LLDNELRGPF NMVSPYPVRN EQFAHALGHA
LHRPAILRVP ATAIRLLMGE SSVLVLGGQR ALPKRLEEAG FAFRWYDLEE ALADVVR
//
