ID D3IHU8_9BACT Unreviewed; 787 AA.
AC D3IHU8;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE SubName: Full=Glutamate synthase (NADPH), homotetrameric {ECO:0000313|EMBL:EFC69594.1};
DE EC=1.4.1.13 {ECO:0000313|EMBL:EFC69594.1};
GN Name=gltA {ECO:0000313|EMBL:EFC69594.1};
GN ORFNames=HMPREF0670_00917 {ECO:0000313|EMBL:EFC69594.1};
OS Prevotella sp. oral taxon 317 str. F0108.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=575615 {ECO:0000313|EMBL:EFC69594.1, ECO:0000313|Proteomes:UP000003829};
RN [1] {ECO:0000313|EMBL:EFC69594.1, ECO:0000313|Proteomes:UP000003829}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0108 {ECO:0000313|EMBL:EFC69594.1,
RC ECO:0000313|Proteomes:UP000003829};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Feldgarden M., Earl A., Young S.K., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J.,
RA Yandava C., Izard J., Baranova O.V., Blanton J.M., Tanner A.C.,
RA Dewhirst F.E., Haas B., Nusbaum C., Birren B.;
RT "The Genome Sequence of Prevotella sp. Oral Taxon 317 strain F0108.";
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GG740072; EFC69594.1; -; Genomic_DNA.
DR RefSeq; WP_009230019.1; NZ_GG740072.1.
DR AlphaFoldDB; D3IHU8; -.
DR eggNOG; COG0493; Bacteria.
DR eggNOG; COG0543; Bacteria.
DR HOGENOM; CLU_011095_1_0_10; -.
DR Proteomes; UP000003829; Unassembled WGS sequence.
DR GO; GO:0004355; F:glutamate synthase (NADPH) activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR CDD; cd06219; DHOD_e_trans_like1; 1.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR019480; Dihydroorotate_DH_Fe-S-bd.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR009051; Helical_ferredxn.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR InterPro; IPR006004; SudA-like.
DR NCBIfam; TIGR01316; gltA; 1.
DR PANTHER; PTHR42783; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR PANTHER; PTHR42783:SF3; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR Pfam; PF10418; DHODB_Fe-S_bind; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR PROSITE; PS51384; FAD_FR; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Oxidoreductase {ECO:0000313|EMBL:EFC69594.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003829}.
FT DOMAIN 1..95
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
FT COILED 260..287
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 787 AA; 85342 MW; 8C3FF8FA0C361D50 CRC64;
MNKIIRKEQF SEKVYRFDIE APLIAKSRKA GNFVIVRVGD KGERMPLTIA DADTTKGTIT
LVVQKVGLSS IKLCNLNEGE YVTDVVGPLG NPTHIENFGT VVCAGGGVGV APMLPIIRAL
KAAGNRVLSV LAGRSKDLII LEDEVRQSSD EVIIMTDDGS YGEQGVVTVG IEKFINAEHI
DRAFAIGPAI MMKFCCLLTQ KYNIPTDVSL NTIMVDGTGM CGACRLTIGG KTKFVCIDGP
EFDGALVDWD EMFKRMGTFK KAESEELQRY NDHIEQVEER VAQTVSDITM DVEPTTEGID
VLTDRNAEWR KELRASMKPK ERTGIHRVEM PELDPVYRAT SRVEEVNKGL TKELALMEAK
RCLDCAKPTC MEGCPVSINI PSFIKNIERG QFLAAAKVLK DTSALPAVCG RVCPQEKQCE
SRCVHLKMNE PAVAIGYLER FAADYERESG NISVPELAPA NGIKIAVVGS GPAGLSFAGD
MAKFGYDVTV FEALHEVGGV LKYGIPEFRL PNTIVDVEID NLKKMGVKFI TDCIVGKTIS
VDDLEEQGYK GIFVGSGAGL PNFMGIPGEN AINIMSSNEY LTRVNLMDAA NPNTDTPINL
GKRVMVVGGG NTAMDSCRTA KRLGAEVTLV YRRSEAEMPA RLEEVKHAKE EGIDFLTLHN
PLEYLADEQG AVKAAVLQVM ELGEPDASGR RSPQPIEGVT KTLDVDQVIV AVGVSPNPLV
PNSIRGLELG RKNTIVVNEG MQSSRPEIYA GGDIVRGGAT VILAMGDGRK AAASMHKQLT
EELQLAI
//
