ID D3LN52_MICLU Unreviewed; 533 AA.
AC D3LN52;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612};
DE EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612};
GN Name=pgi {ECO:0000313|EMBL:EFD50999.1};
GN ORFNames=HMPREF0569_0810 {ECO:0000313|EMBL:EFD50999.1};
OS Micrococcus luteus SK58.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Micrococcus.
OX NCBI_TaxID=596312 {ECO:0000313|EMBL:EFD50999.1, ECO:0000313|Proteomes:UP000002933};
RN [1] {ECO:0000313|EMBL:EFD50999.1, ECO:0000313|Proteomes:UP000002933}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK58 {ECO:0000313|EMBL:EFD50999.1,
RC ECO:0000313|Proteomes:UP000002933};
RA Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Strausberg R.L., Nelson K.E.;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate;
CC Xref=Rhea:RHEA:11816, ChEBI:CHEBI:57634, ChEBI:CHEBI:58225;
CC EC=5.3.1.9; Evidence={ECO:0000256|RuleBase:RU000612};
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC phosphate and glycerone phosphate from D-glucose: step 2/4.
CC {ECO:0000256|RuleBase:RU000612}.
CC -!- SIMILARITY: Belongs to the GPI family. {ECO:0000256|RuleBase:RU000612}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFD50999.1}.
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DR EMBL; ADCD01000046; EFD50999.1; -; Genomic_DNA.
DR RefSeq; WP_002855641.1; NZ_ADCD01000046.1.
DR AlphaFoldDB; D3LN52; -.
DR UniPathway; UPA00109; UER00181.
DR Proteomes; UP000002933; Unassembled WGS sequence.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR001672; G6P_Isomerase.
DR InterPro; IPR046348; SIS_dom_sf.
DR PANTHER; PTHR11469; GLUCOSE-6-PHOSPHATE ISOMERASE; 1.
DR PANTHER; PTHR11469:SF1; GLUCOSE-6-PHOSPHATE ISOMERASE; 1.
DR Pfam; PF00342; PGI; 1.
DR PRINTS; PR00662; G6PISOMERASE.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51463; P_GLUCOSE_ISOMERASE_3; 1.
PE 3: Inferred from homology;
KW Gluconeogenesis {ECO:0000256|ARBA:ARBA00022432,
KW ECO:0000256|RuleBase:RU000612};
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152, ECO:0000256|RuleBase:RU000612};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU000612}.
SQ SEQUENCE 533 AA; 55122 MW; B23BC723AF0B2077 CRC64;
MSTLGLTATG AALEAIDRHL PALLQDRVAS RLGAQDADLW GAPARDEAAK RLGWIDLFED
SRALVPHIAQ LTRELRAEGV DRVVLAGMGG SSLAPEVIAA TAGVELEVLD STDPLQVSRA
LERDLERTVL VVSSKSGSTV ETDSQRRVVE AAFRDAGIDP RTRLVAVTDP GSPLHAACES
AGWRAVFTAD PTVGGRFSAL AAFGLVPTGL AGVDVAALLD DAEAVLDLLT ADDEDNPGLQ
LGAALGGTQP LRDKLVFADH GSGIAGLPAW IEQLIAESTG KDGTGLLPVV VAPGDPETAW
DAPDLLQVQL VGEDDVAAPG HGVQVAGSLG AQLLLWEVAT AVAGRLLGIN PFDQPDVEAA
KAAARTLLDG PAAERTADGE VEGVEVSGPA SVTSAPDLAG VLRATAALVP EDGYLAVHAY
LSRHDDAELE GLRADLADLV GRPVTFGWGP RFLHSTGQFH KGGPAVGVFL QITGDAGLDL
EVPGRPFSLG RLIAAQAAGD ARVLGDLDRP VVTLHLRRRD AGIEALRSAV RGR
//
