ID   D3LTF9_9FIRM            Unreviewed;       339 AA.
AC   D3LTF9;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   24-JAN-2024, entry version 40.
DE   SubName: Full=3-deoxy-7-phosphoheptulonate synthase {ECO:0000313|EMBL:EFD94498.1};
DE            EC=2.5.1.54 {ECO:0000313|EMBL:EFD94498.1};
GN   Name=aroF {ECO:0000313|EMBL:EFD94498.1};
GN   ORFNames=HMPREF0889_0559 {ECO:0000313|EMBL:EFD94498.1};
OS   Megasphaera genomosp. type_1 str. 28L.
OC   Bacteria; Bacillota; Negativicutes; Veillonellales; Veillonellaceae;
OC   Megasphaera.
OX   NCBI_TaxID=699218 {ECO:0000313|EMBL:EFD94498.1, ECO:0000313|Proteomes:UP000003242};
RN   [1] {ECO:0000313|Proteomes:UP000003242}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=28L {ECO:0000313|Proteomes:UP000003242};
RA   Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA   Strausberg R.L., Nelson K.E.;
RT   "Sequence of Clostridiales genomosp. BVAB3 str. UPII9-5.";
RL   Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFD94498.1}.
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DR   EMBL; ADGP01000009; EFD94498.1; -; Genomic_DNA.
DR   RefSeq; WP_009369522.1; NZ_ADGP01000009.1.
DR   AlphaFoldDB; D3LTF9; -.
DR   STRING; 699218.HMPREF0889_0559; -.
DR   eggNOG; COG2876; Bacteria.
DR   OrthoDB; 9780456at2; -.
DR   Proteomes; UP000003242; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016832; F:aldehyde-lyase activity; IEA:InterPro.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR041071; DAHP_snth_FXD.
DR   InterPro; IPR006268; DAHP_syn_2.
DR   NCBIfam; TIGR01361; DAHP_synth_Bsub; 1.
DR   PANTHER; PTHR43018; PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE; 1.
DR   PANTHER; PTHR43018:SF1; PROTEIN AROA(G); 1.
DR   Pfam; PF18152; DAHP_snth_FXD; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
PE   4: Predicted;
KW   Transferase {ECO:0000313|EMBL:EFD94498.1}.
FT   DOMAIN          1..66
FT                   /note="DAHP synthase ferredoxin-like"
FT                   /evidence="ECO:0000259|Pfam:PF18152"
FT   DOMAIN          84..331
FT                   /note="DAHP synthetase I/KDSA"
FT                   /evidence="ECO:0000259|Pfam:PF00793"
SQ   SEQUENCE   339 AA;  37343 MW;  E58C9CD761E8B7B1 CRC64;
     MIIVIKEGTE AEKMEALQEE LRTQGVEVDV SRGKRKTLLG LIGNTSRINQ SHVKSLDFVE
     QVIRIDEPYT RASRAFHPED TVVTLANGTQ IGGKKLTVMA GPCSVETPKQ MTTLAAHMRK
     TGAAVMRGGA FKPRTSPYSF QGLKETGLEM LCRAARKEKL PVVTEIMSAD KLDVFLQQEV
     DIIQIGARNM QNFELLRAVG KTRKPILLKR GLSATIEEWL MAAEYIMAGG NSNVILCERG
     IRTYETYTRN TLDLSAVLAV KRQSHLPIIV DPSHATGKRW MVPALAKAAI VAGADGIMVE
     VHNNPSEALC DGEESITPDM FDELMQSLRQ LAPICGREL
//