ID D3SAP8_THISK Unreviewed; 608 AA.
AC D3SAP8;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Oxaloacetate decarboxylase alpha subunit {ECO:0000313|EMBL:ADC72103.1};
GN OrderedLocusNames=TK90_1606 {ECO:0000313|EMBL:ADC72103.1};
OS Thioalkalivibrio sp. (strain K90mix).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Ectothiorhodospiraceae; Thioalkalivibrio.
OX NCBI_TaxID=396595 {ECO:0000313|EMBL:ADC72103.1, ECO:0000313|Proteomes:UP000009099};
RN [1] {ECO:0000313|Proteomes:UP000009099}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K90mix {ECO:0000313|Proteomes:UP000009099};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Foster B., Sun H., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Ivanova N., Sorokin D.Y., Muyzer G., Woyke T.;
RT "Complete sequence of chromosome of Thioalkalivibrio sp. K90mix.";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADC72103.1, ECO:0000313|Proteomes:UP000009099}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K90mix {ECO:0000313|EMBL:ADC72103.1,
RC ECO:0000313|Proteomes:UP000009099};
RX PubMed=22675584; DOI=10.4056/sigs.2315092;
RA Muyzer G., Sorokin D.Y., Mavromatis K., Lapidus A., Foster B., Sun H.,
RA Ivanova N., Pati A., D'haeseleer P., Woyke T., Kyrpides N.C.;
RT "Complete genome sequence of Thioalkalivibrio sp. K90mix.";
RL Stand. Genomic Sci. 5:341-355(2011).
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DR EMBL; CP001905; ADC72103.1; -; Genomic_DNA.
DR RefSeq; WP_012982984.1; NC_013889.1.
DR AlphaFoldDB; D3SAP8; -.
DR STRING; 396595.TK90_1606; -.
DR KEGG; tkm:TK90_1606; -.
DR eggNOG; COG0511; Bacteria.
DR eggNOG; COG5016; Bacteria.
DR HOGENOM; CLU_000395_4_2_6; -.
DR OrthoDB; 9760256at2; -.
DR Proteomes; UP000009099; Chromosome.
DR GO; GO:0008948; F:oxaloacetate decarboxylase activity; IEA:InterPro.
DR GO; GO:0004736; F:pyruvate carboxylase activity; IEA:UniProt.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR CDD; cd06850; biotinyl_domain; 1.
DR CDD; cd07937; DRE_TIM_PC_TC_5S; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR001882; Biotin_BS.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR003379; Carboxylase_cons_dom.
DR InterPro; IPR005776; OadA.
DR InterPro; IPR000891; PYR_CT.
DR InterPro; IPR011053; Single_hybrid_motif.
DR NCBIfam; TIGR01108; oadA; 1.
DR PANTHER; PTHR45266; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR PANTHER; PTHR45266:SF3; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR Pfam; PF00364; Biotin_lipoyl; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR Pfam; PF02436; PYC_OADA; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR SUPFAM; SSF89000; post-HMGL domain-like; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
DR PROSITE; PS00188; BIOTIN; 1.
DR PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 4: Predicted;
KW Biotin {ECO:0000256|ARBA:ARBA00023267}.
FT DOMAIN 4..264
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
FT DOMAIN 529..604
FT /note="Lipoyl-binding"
FT /evidence="ECO:0000259|PROSITE:PS50968"
FT REGION 513..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 608 AA; 66082 MW; A0F71683386954B8 CRC64;
MDRVHITDVT LRDGHQSLIA TRMRTEDMLP ICEQMDAIGF HSLEAWGGAT FDACVRFLKE
DPWERLHQLK GALPNTPLQM LLRGQNLLGY RHYADDVVRA FVERSVAGGI DIIRIFDAMN
DARNLRTAIE ATRKAGGHAQ GTLCYTTGPV HSAAQFVALA RELVAMGAQS IAIKDMAGLL
TPTATRELVT ELVDALDVPI HLHAHATSGL SELCHWQAIE AGCRHIETAI SAFAGGTSHP
PTESLVAALS STEHDTGLDL VALQKIGLYF HEVRKKYQRF ESEYTGVDTR VQVNQVPGGM
ISNLANQLRD QNALDRFDAV LEEIPRVRED LGYPPLVTPT SQIVGTQAVM NVLAGERYKT
ITNEVKQYLT GHYGRAPGPI NRVIQRKAIG NAEVIDVRPA DLLKPEMDHL TREIGDLAQG
PEDVLTFALF PEVGRSFLEQ RRNGTLEPEP LNLPENTQAG CPAPVEFNVT FHGESYHIRV
NGSGHHREDT RPMYVTIDGM PEDVLIETLD TIDTAGGGGA ESPRTGKKSR RATRPGDVTT
SMPGTVIDVL VAEGDTVEAG QPVLVLEAMK MESEIAAPIA GTVRAVNVAK GAAANPDDAL
IEIDSPDG
//
