ID D3SUE8_NATMM Unreviewed; 834 AA.
AC D3SUE8;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=CARDB domain-containing protein {ECO:0000259|Pfam:PF07705};
GN OrderedLocusNames=Nmag_1630 {ECO:0000313|EMBL:ADD05206.1};
GN ORFNames=C500_20671 {ECO:0000313|EMBL:ELY23242.1};
OS Natrialba magadii (strain ATCC 43099 / DSM 3394 / CCM 3739 / CIP 104546 /
OS IAM 13178 / JCM 8861 / NBRC 102185 / NCIMB 2190 / MS3) (Natronobacterium
OS magadii).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrialba.
OX NCBI_TaxID=547559 {ECO:0000313|EMBL:ADD05206.1, ECO:0000313|Proteomes:UP000001879};
RN [1] {ECO:0000313|Proteomes:UP000001879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43099 / DSM 3394 / CCM 3739 / CIP 104546 / IAM 13178 / JCM
RC 8861 / NBRC 102185 / NCIMB 2190 / MS3
RC {ECO:0000313|Proteomes:UP000001879};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Davenport K., Saunders E., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Mikhailova N., De Castro R.E.,
RA Maupin-Furlow J.A., Woyke T.;
RT "Complete sequence of chromosome of Natrialba magadii ATCC 43099.";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADD05206.1, ECO:0000313|Proteomes:UP000001879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43099 {ECO:0000313|EMBL:ADD05206.1}, and ATCC 43099 / DSM
RC 3394 / CCM 3739 / CIP 104546 / IAM 13178 / JCM 8861 / NBRC 102185 /
RC NCIMB 2190 / MS3 {ECO:0000313|Proteomes:UP000001879};
RX PubMed=22559199; DOI=10.1186/1471-2164-13-165;
RA Siddaramappa S., Challacombe J.F., Decastro R.E., Pfeiffer F., Sastre D.E.,
RA Gimenez M.I., Paggi R.A., Detter J.C., Davenport K.W., Goodwin L.A.,
RA Kyrpides N., Tapia R., Pitluck S., Lucas S., Woyke T., Maupin-Furlow J.A.;
RT "A comparative genomics perspective on the genetic content of the
RT alkaliphilic haloarchaeon Natrialba magadii ATCC 43099T.";
RL BMC Genomics 13:165-165(2012).
RN [3] {ECO:0000313|EMBL:ELY23242.1, ECO:0000313|Proteomes:UP000011543}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43099 / DSM 3394 / CCM 3739 / CIP 104546 / IAM 13178 / JCM
RC 8861 / NBRC 102185 / NCIMB 2190 / MS3
RC {ECO:0000313|Proteomes:UP000011543}, and MS-3
RC {ECO:0000313|EMBL:ELY23242.1};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
RN [4] {ECO:0000313|EMBL:ADD05206.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 43099 {ECO:0000313|EMBL:ADD05206.1};
RA Pfeiffer F.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
CC Membrane {ECO:0000256|ARBA:ARBA00004370}. Secreted, cell wall, S-layer
CC {ECO:0000256|ARBA:ARBA00004237}.
CC -!- SIMILARITY: Belongs to the halobacterial S-layer protein family.
CC {ECO:0000256|ARBA:ARBA00009327}.
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DR EMBL; CP001932; ADD05206.1; -; Genomic_DNA.
DR EMBL; AOHS01000063; ELY23242.1; -; Genomic_DNA.
DR RefSeq; WP_004217501.1; NZ_AOHS01000063.1.
DR AlphaFoldDB; D3SUE8; -.
DR PaxDb; 547559-Nmag_1630; -.
DR GeneID; 8824465; -.
DR KEGG; nmg:Nmag_1630; -.
DR PATRIC; fig|547559.17.peg.4082; -.
DR eggNOG; arCOG06273; Archaea.
DR HOGENOM; CLU_011657_0_0_2; -.
DR OrthoDB; 169503at2157; -.
DR Proteomes; UP000001879; Chromosome.
DR Proteomes; UP000011543; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030115; C:S-layer; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR011635; CARDB.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR026371; PGF_CTERM.
DR InterPro; IPR026452; Surf_glycop_sig_pep.
DR NCBIfam; TIGR04207; halo_sig_pep; 1.
DR NCBIfam; TIGR04126; PGF_CTERM; 1.
DR Pfam; PF07705; CARDB; 1.
DR Pfam; PF18204; PGF-CTERM; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Reference proteome {ECO:0000313|Proteomes:UP000001879};
KW S-layer {ECO:0000256|ARBA:ARBA00022601};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 678..756
FT /note="CARDB"
FT /evidence="ECO:0000259|Pfam:PF07705"
FT REGION 416..438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 717..740
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 753..813
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 753..808
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 834 AA; 89784 MW; 8A9D3B60EA216F7B CRC64;
MTSNTTFREK GRAVFLAALM VLSVVAMSAT FAGAAAAFNS DTYDEGPTIT SSENLDDVWV
GQEITLVDDD WDGDFVSIAE GPETTGEDPD TVTTVGFDDD EVTFNTEELV EGEIYHIYAH
GDTTETFEFE DDAFEATSEN LDVSFESDTV AEDGTLDLEV SSDRPEQSLN ISSDDFDADE
LDDIFNSEDV DVYDHGDEDV ITLKTVEDDD EIPANFLDVE SGEYEFEFDV TDSIDSDNAT
IEVRDSDADR EFVNGPYTQQ QGDEFNITVD HDDTNDAFVT IGDYEDAGYE VGLFVEDTEG
DHDEINITFN AHEAGQGDEY DAISAQQEDV NLEIAYMQVV DSDTIHINDD YFDESDLDSE
YDTVEDDITD SSATPTATLD NPLAATDYEL NVGDGYEVDD GAVEFTDRSD SSFINLEPVG
APGDVTTHTA PEDDSMSDLD DFEDATVTAT DSFAEDDYLL LTVEDAGLTG AFPSDDDVSV
GANTDDDEGL SALDIELEIE QTDVASNLGD EVWNTSDEAD NDLEVSLVNG GDYDGELLIF
NIDTEFDEGD YEWTLLFDEG DYIDEDEEVE IEGEFAVEER DVTLNAVDEV PNVDGAELSG
DTNVAPGTEI DMVSSATGEF VLTDDPVVAD DYSFTGAFDF SDYEPGIEFD VEAEEPEGAS
DDFTAELVDG DGPVINVDTD APDEVKVGDD ATLDVTISNN GGATAEDVEI GVVIDGENVD
EDTESLDADE SWTSSYDIPT DVAGDVEWSV TADDAEDDGV TTVSEKDDTD DDKSDDDKSD
DDGADDDGAA DDGAAADDGT DDGETDDDGS PGFGVAVALA ALLGAAMLAL RKQN
//
