ID D3YV69_MOUSE Unreviewed; 175 AA.
AC D3YV69;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=RAB6A, member RAS oncogene family {ECO:0000313|Ensembl:ENSMUSP00000102663.2};
GN Name=Rab6a {ECO:0000313|Ensembl:ENSMUSP00000102663.2,
GN ECO:0000313|MGI:MGI:894313};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000102663.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000102663.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000102663.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000102663.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000102663.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC {ECO:0000256|ARBA:ARBA00006270}.
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DR AlphaFoldDB; D3YV69; -.
DR SMR; D3YV69; -.
DR jPOST; D3YV69; -.
DR MaxQB; D3YV69; -.
DR PeptideAtlas; D3YV69; -.
DR ProteomicsDB; 310441; -.
DR Antibodypedia; 4093; 334 antibodies from 33 providers.
DR Ensembl; ENSMUST00000107048.8; ENSMUSP00000102663.2; ENSMUSG00000030704.15.
DR AGR; MGI:894313; -.
DR MGI; MGI:894313; Rab6a.
DR VEuPathDB; HostDB:ENSMUSG00000030704; -.
DR GeneTree; ENSGT00940000154769; -.
DR ChiTaRS; Rab6a; mouse.
DR Proteomes; UP000000589; Chromosome 7.
DR Bgee; ENSMUSG00000030704; Expressed in primary motor cortex and 271 other cell types or tissues.
DR ExpressionAtlas; D3YV69; baseline and differential.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd01861; Rab6; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR47977:SF92; RAB6A, MEMBER RAS ONCOGENE FAMILY; 1.
DR PANTHER; PTHR47977; RAS-RELATED PROTEIN RAB; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00176; RAN; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
DR PROSITE; PS51420; RHO; 1.
PE 1: Evidence at protein level;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Proteomics identification {ECO:0007829|EPD:D3YV69,
KW ECO:0007829|MaxQB:D3YV69};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
SQ SEQUENCE 175 AA; 19962 MW; 1667A3BFAE94E983 CRC64;
MYDSFDNTYQ ATIGIDFLSK TMYLEDRTIR LQLWDTAGQE RFRSLIPSYI RDSAAAVVVY
DITNVNSFQQ TTKWIDDVRT ERGSDVIIML VGNKTDLADK RQVSIEEGER KAKELNVMFI
ETSAKAGYNV KQLFRRVAAA LPGMESTQDR SREDMIDIKL EKPQEQPVNE GGCSC
//
