ID D3YWJ5_MOUSE Unreviewed; 188 AA.
AC D3YWJ5;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE RecName: Full=Tumor necrosis factor alpha-induced protein 8 {ECO:0000256|ARBA:ARBA00040051};
GN Name=Tnfaip8 {ECO:0000313|Ensembl:ENSMUSP00000120712.3,
GN ECO:0000313|MGI:MGI:2147191};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000120712.3, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000120712.3, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000120712.3,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000120712.3}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000120712.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TNFAIP8 family.
CC {ECO:0000256|ARBA:ARBA00038267}.
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DR RefSeq; NP_001171230.1; NM_001177759.1.
DR AlphaFoldDB; D3YWJ5; -.
DR SMR; D3YWJ5; -.
DR EPD; D3YWJ5; -.
DR jPOST; D3YWJ5; -.
DR MaxQB; D3YWJ5; -.
DR PeptideAtlas; D3YWJ5; -.
DR ProteomicsDB; 326763; -.
DR Antibodypedia; 25539; 304 antibodies from 32 providers.
DR DNASU; 106869; -.
DR Ensembl; ENSMUST00000148989.3; ENSMUSP00000120712.3; ENSMUSG00000062210.14.
DR GeneID; 106869; -.
DR UCSC; uc012bcy.1; mouse.
DR AGR; MGI:2147191; -.
DR MGI; MGI:2147191; Tnfaip8.
DR VEuPathDB; HostDB:ENSMUSG00000062210; -.
DR GeneTree; ENSGT00390000003488; -.
DR OMA; YPDTMHS; -.
DR OrthoDB; 5401401at2759; -.
DR BioGRID-ORCS; 106869; 3 hits in 78 CRISPR screens.
DR ChiTaRS; Tnfaip8; mouse.
DR Proteomes; UP000000589; Chromosome 18.
DR Bgee; ENSMUSG00000062210; Expressed in gastrula and 263 other cell types or tissues.
DR ExpressionAtlas; D3YWJ5; baseline and differential.
DR Genevisible; D3YWJ5; MM.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR Gene3D; 1.20.1440.160; Tumor necrosis factor alpha-induced protein 8-like; 1.
DR InterPro; IPR008477; TNFAIP8-like.
DR InterPro; IPR038355; TNFAIP8_sf.
DR PANTHER; PTHR12757:SF3; TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8; 1.
DR PANTHER; PTHR12757; TUMOR NECROSIS FACTOR INDUCED PROTEIN; 1.
DR Pfam; PF05527; DUF758; 1.
PE 1: Evidence at protein level;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Proteomics identification {ECO:0007829|EPD:D3YWJ5,
KW ECO:0007829|MaxQB:D3YWJ5};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT COILED 41..68
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 188 AA; 21820 MW; 238004D142075390 CRC64;
MATDVFNSKN LAVQAQKKIL GKMVSKSIAT TLIDDTSSEV LDELYRVTKE YTQNKKEAER
VIKNLIKTVI KLAVLHRNNQ FNQDELALME KFKKKVHQLA MTVVSFHQVE YTFDRNVLSR
LLNECRELLH EIIQRHLTAK SHGRVNNVFD HFSDCDFLAA LYNPFGKFKP HLQKLCDGIN
KMLDEENI
//
