ID D3Z0R8_MOUSE Unreviewed; 822 AA.
AC D3Z0R8;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE SubName: Full=Tetratricopeptide repeat domain 7 {ECO:0000313|Ensembl:ENSMUSP00000115351.2};
GN Name=Ttc7 {ECO:0000313|Ensembl:ENSMUSP00000115351.2,
GN ECO:0000313|MGI:MGI:1920999};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000115351.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0007829|PubMed:19144319}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19144319; DOI=10.1016/j.immuni.2008.11.006;
RA Trost M., English L., Lemieux S., Courcelles M., Desjardins M.,
RA Thibault P.;
RT "The phagosomal proteome in interferon-gamma-activated macrophages.";
RL Immunity 30:143-154(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000115351.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000115351.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [4] {ECO:0000313|Ensembl:ENSMUSP00000115351.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000115351.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; D3Z0R8; -.
DR SMR; D3Z0R8; -.
DR EPD; D3Z0R8; -.
DR jPOST; D3Z0R8; -.
DR MaxQB; D3Z0R8; -.
DR PeptideAtlas; D3Z0R8; -.
DR ProteomicsDB; 351172; -.
DR Antibodypedia; 47406; 130 antibodies from 21 providers.
DR Ensembl; ENSMUST00000125875.8; ENSMUSP00000115351.2; ENSMUSG00000036918.17.
DR UCSC; uc008duu.1; mouse.
DR AGR; MGI:1920999; -.
DR MGI; MGI:1920999; Ttc7.
DR VEuPathDB; HostDB:ENSMUSG00000036918; -.
DR GeneTree; ENSGT00940000158638; -.
DR ChiTaRS; Ttc7; mouse.
DR Proteomes; UP000000589; Chromosome 17.
DR Bgee; ENSMUSG00000036918; Expressed in granulocyte and 134 other cell types or tissues.
DR ExpressionAtlas; D3Z0R8; baseline and differential.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR045819; TTC7_N.
DR PANTHER; PTHR23083:SF475; TETRATRICOPEPTIDE REPEAT PROTEIN 7A; 1.
DR PANTHER; PTHR23083; TETRATRICOPEPTIDE REPEAT PROTEIN, TPR; 1.
DR Pfam; PF13432; TPR_16; 1.
DR Pfam; PF19440; TTC7_N; 1.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:D3Z0R8,
KW ECO:0007829|MaxQB:D3Z0R8};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 9..404
FT /note="Tetratricopeptide repeat protein 7 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF19440"
FT REPEAT 745..778
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 790..822
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 822 AA; 91944 MW; 338FC6BDBA2AAD80 CRC64;
MAAKGAHGTH LKVESEVERC RAEGQWDRMF ELARHLQMLG ISGGGSSNRR NSPSGRFTTL
DTDDFVKLLL AEALLEQCLK DNHDKIKNSI PLLEKTDHRL NEAKDHLSSL LNNGKLPPQY
MCEAMLILGK LHYVEGSYRD AVSMYARAGI DDISVENKPL YQMRLLSEAF VIKGLSLERL
PNSVASHIRL TEREEEVVAC FERASWVAQV FLQELEKTSN NSTSRHLKGS LSPDYELSYF
LEAALQSAYV KNLKKGNIVK GMRELREILR TVETKATQNF KVVAAKHLAG VLLHSLSEDC
YWSPLSHPLP EFMNKEENSF VTQTLRKPHL YEGDNLYCPK DNIEEALLLL LISESMATRD
VVLSRAPEQA EDRKVSLQNA SAIYDLLSIT LGRRGQYVML SECLERAMKC AFGEFHLWYQ
VALSMVACGK SAYAVSLLRE CMKLQPSDPT VPLMAAKVCI GSLHWLEEAE HFATVVIGLG
EEAGESLPKG YLALGLTYSL QATDATLKSK QDELHRKALQ TLERARELAP DDPQIIFYVA
LQLALVRQIS SAMERLQEAL TMCRDDANAL HLLALLFSAQ KYYQHALDVI NMAITEHPEN
FNLMFTKVKL EQVLKGPEEA LVTCRQMLRL WQTLYNFSQL GGLEKDGSFE GLTVKKQNGI
HLTLPDAHDA DSGSRRASSI AASRLEEAMS ELTLTTSVLK QGPMQLWTTL EQIWLQAAEL
FMEQRQLKEA GFCIQEAAGL FPTSHSVLYM RGRLAEVKGS FEEAKQLYKE ALTVNPDGVR
IMHSLVSHSP LPRPPFSSPS PRQVPAAAAA DDDDVDDASG HL
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