ID D4AZU9_ARTBC Unreviewed; 1134 AA.
AC D4AZU9;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Ion transport domain-containing protein {ECO:0000259|Pfam:PF00520};
GN ORFNames=ARB_01719 {ECO:0000313|EMBL:EFE31324.1};
OS Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton
OS mentagrophytes).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=663331 {ECO:0000313|EMBL:EFE31324.1, ECO:0000313|Proteomes:UP000008866};
RN [1] {ECO:0000313|Proteomes:UP000008866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4681 / CBS 112371 {ECO:0000313|Proteomes:UP000008866};
RX PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7;
RA Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S.,
RA Staib P., Heidel A., Felder M., Petzold A., Szafranski K., Feuermann M.,
RA Pedruzzi I., Priebe S., Groth M., Winkler R., Li W., Kniemeyer O.,
RA Schroeckh V., Hertweck C., Hube B., White T.C., Platzer M., Guthke R.,
RA Heitman J., Woestemeyer J., Zipfel P.F., Monod M., Brakhage A.A.;
RT "Comparative and functional genomics provide insights into the
RT pathogenicity of dermatophytic fungi.";
RL Genome Biol. 12:R7.1-R7.16(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFE31324.1}.
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DR EMBL; ABSU01000022; EFE31324.1; -; Genomic_DNA.
DR RefSeq; XP_003011964.1; XM_003011918.1.
DR AlphaFoldDB; D4AZU9; -.
DR STRING; 663331.D4AZU9; -.
DR GeneID; 9519288; -.
DR KEGG; abe:ARB_01719; -.
DR eggNOG; ENOG502QU70; Eukaryota.
DR HOGENOM; CLU_003613_0_0_1; -.
DR OMA; NSFMRIV; -.
DR OrthoDB; 1386366at2759; -.
DR Proteomes; UP000008866; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR InterPro; IPR005821; Ion_trans_dom.
DR PANTHER; PTHR35859:SF4; MEMBRANE CHANNEL PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11300)-RELATED; 1.
DR PANTHER; PTHR35859; NONSELECTIVE CATION CHANNEL PROTEIN; 1.
DR Pfam; PF00520; Ion_trans; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008866};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 333..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..444
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 465..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 499..518
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 527..548
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 580..600
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 338..557
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 1..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 743..775
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 796..955
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1066..1134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..37
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..63
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 829..849
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 850..879
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 880..894
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 908..954
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1076..1092
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1093..1116
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1134 AA; 128127 MW; 9434F6AB37A8E40B CRC64;
MFSSLSRPMR KQRLGLFSSS RPVEQNERDD RDFEAAAQTE PEAASEENIE DYEIEEEQYE
DGPDSESQAP LLPMFSVHLD AIPVYQLTHD LRLLISSRCE TTLTWDQLRS PQVSQFLLKP
IQQIIHSRHL TKATLYALMV NCLQFDKEAT SNPGISGASR TRAMVCELLA IKLLKEYTVR
SLIDALSYDF HPLQGQASKL STGTSNGRPW DSNQGSRALL KDVRISCLEI AIRAQAKRFL
AHPVVVQQLE ALWAGTIVFY SGADSLHRQP LPDAPLQFHG YGSIYRRGYR ADTKGIPSVQ
NKHISRRSVS IYDPRDASLF KLSRLRVPRY RQLLSTLSYA ILLCLFLILL QKRPLHLTGF
EMVFWFWSAG FMLDEIVGFN EQGFSLYLMS FWNMFDVGIL VLLLIYYVLR LYGAIVPQNQ
KAYAAGLAYD TLAANAVLLL PRLFSVLDHY RYFSQLLIAF RMMAADLIAV LILIIIACSG
FFVAFTFSFG DTNASPSSVA YALFQMVMGF TPAAWTLWDR YNLLGKIILT LFLFICHFLV
ITILITILTN SFMAIVQNAH EEHQFLFAVN TISMVKSDAL FSYVAPTNVL AWAITPLRFV
IPFRRFLKLN RTVIKITHFP ILFCIYLYER TILRPAAIEP TDLIRGRFNP VDPIGDQERS
FSPFTPRARF RVREPSVATH QKDRALDQVF DLSGEGTTYQ EPRRSRARQR LSTANVSNWM
RNIGDGSSRA PPEDQDRKVV EDLEARRVWP GQSQRRRRNR GMSGHNFFTD TTRSFASDPE
DFMSVAFDTT EVNKGPRPRV YLQREETITA PTQTDVEVQG DDELSSDENG GGDSSRDGDL
PDHRKTQETV FPTENMLESS VDSSPMLSRP STAKRFSRRN SPSRTPRTPR RHHSRNPSAA
TILYNPVPPE ATKSTTGSKP PSPKQKGKTG TTTPNRRRLQ SNLKSSQLTT RPRPIPQPTA
AAFSVPDHGI QWSLNNLPSQ RRRPLSLTLG LGSDIGDNEA VGGGFVGGVP GSFNTQMAYA
MGGMQQDRGN DNRDMLSRLV LARMKTLEES FRDVLNEVKD LRHVPGRKER VRPVASRRQN
TTATSSPKQG VDTPTREESR RGGEKKLQGG FEPKDEPLSE EESESSSESR LRSF
//
