ID D4B255_ARTBC Unreviewed; 539 AA.
AC D4B255;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 13-SEP-2023, entry version 56.
DE RecName: Full=DNA primase {ECO:0000256|RuleBase:RU003514};
DE EC=2.7.7.- {ECO:0000256|RuleBase:RU003514};
GN ORFNames=ARB_02538 {ECO:0000313|EMBL:EFE30616.1};
OS Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton
OS mentagrophytes).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=663331 {ECO:0000313|EMBL:EFE30616.1, ECO:0000313|Proteomes:UP000008866};
RN [1] {ECO:0000313|Proteomes:UP000008866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4681 / CBS 112371 {ECO:0000313|Proteomes:UP000008866};
RX PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7;
RA Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S.,
RA Staib P., Heidel A., Felder M., Petzold A., Szafranski K., Feuermann M.,
RA Pedruzzi I., Priebe S., Groth M., Winkler R., Li W., Kniemeyer O.,
RA Schroeckh V., Hertweck C., Hube B., White T.C., Platzer M., Guthke R.,
RA Heitman J., Woestemeyer J., Zipfel P.F., Monod M., Brakhage A.A.;
RT "Comparative and functional genomics provide insights into the
RT pathogenicity of dermatophytic fungi.";
RL Genome Biol. 12:R7.1-R7.16(2011).
CC -!- SIMILARITY: Belongs to the eukaryotic-type primase small subunit
CC family. {ECO:0000256|ARBA:ARBA00009762, ECO:0000256|RuleBase:RU003514}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFE30616.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ABSU01000028; EFE30616.1; -; Genomic_DNA.
DR RefSeq; XP_003011256.1; XM_003011210.1.
DR AlphaFoldDB; D4B255; -.
DR STRING; 663331.D4B255; -.
DR GeneID; 9523994; -.
DR KEGG; abe:ARB_02538; -.
DR eggNOG; KOG2851; Eukaryota.
DR HOGENOM; CLU_028288_1_0_1; -.
DR OMA; NVTRGFN; -.
DR OrthoDB; 168741at2759; -.
DR Proteomes; UP000008866; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003896; F:DNA primase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd04860; AE_Prim_S; 1.
DR Gene3D; 3.90.920.10; DNA primase, PRIM domain; 1.
DR InterPro; IPR002755; DNA_primase_S.
DR InterPro; IPR014052; DNA_primase_ssu_euk/arc.
DR NCBIfam; TIGR00335; primase_sml; 1.
DR PANTHER; PTHR10536; DNA PRIMASE SMALL SUBUNIT; 1.
DR PANTHER; PTHR10536:SF0; DNA PRIMASE SMALL SUBUNIT; 1.
DR Pfam; PF01896; DNA_primase_S; 1.
DR SUPFAM; SSF56747; Prim-pol domain; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|RuleBase:RU003514};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU003514};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Primosome {ECO:0000256|ARBA:ARBA00022515, ECO:0000256|RuleBase:RU003514};
KW Reference proteome {ECO:0000313|Proteomes:UP000008866};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003514}.
FT REGION 1..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 465..498
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..59
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..75
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 465..487
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 539 AA; 61495 MW; 314DC2AE2E51E636 CRC64;
MEGKDDEVLP DAPPSDNIPK TEDQNGVTKD NKEENDAEVD SPKEEEDTLV KKSLKLENMF
DDDDDDDDDE EFPDSDAVQI PDKPAPSLAQ TDPEFMSAFY QRLFPFKYLF QWLNHGVKPS
TDFGNREFAF TLPNDAYLRY QSFQTADAYV YTFLPQSGFK LTSLHSLHKD VMRLNPSRFE
IGPVYSTNPR DRKTLRKPGA FKPISKELVF DIDLTDYDDI RTCCSKANIC LKCWAFVTMS
IKVIDAALRE DFGFQHILWV YSGRRGAHAW VCDKRARNLP DDRRRAIAGY LEVVRGGSQS
GKRVNLRRPL HPHITRSLDT LREYFASTVL VDQDPFSRPD QAARLIELLP DKTLRAALQK
KWDSAPGRSS SNKWADIDTV AKANSRGLDT KALLEAKQDI VLEYTYPRLD AEVSKKLIHL
LKSPFVVHPG TGRVCVPIDI RKVDDFNPLD TPTLFQLLDE INSWNPSQAS QRDQMPGSDS
GSGQDETDTA AKPRKIQDYE KTSLKPYIDY FRSFVAKLNS DERPAKRERT DDDPNAMEF
//
