ID D4H092_HALVD Unreviewed; 408 AA.
AC D4H092;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=ORC1-type DNA replication protein {ECO:0000256|HAMAP-Rule:MF_01407};
GN Name=orc10 {ECO:0000313|EMBL:ADE05207.1};
GN OrderedLocusNames=HVO_C0001 {ECO:0000313|EMBL:ADE05207.1};
OS Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 /
OS NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii).
OG Plasmid pHV1 {ECO:0000313|EMBL:ADE05207.1,
OG ECO:0000313|Proteomes:UP000008243}.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloferax.
OX NCBI_TaxID=309800 {ECO:0000313|EMBL:ADE05207.1, ECO:0000313|Proteomes:UP000008243};
RN [1] {ECO:0000313|EMBL:ADE05207.1, ECO:0000313|Proteomes:UP000008243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 /
RC VKM B-1768 / DS2 {ECO:0000313|Proteomes:UP000008243};
RX PubMed=20333302; DOI=10.1371/journal.pone.0009605;
RA Hartman A.L., Norais C., Badger J.H., Delmas S., Haldenby S., Madupu R.,
RA Robinson J., Khouri H., Ren Q., Lowe T.M., Maupin-Furlow J.,
RA Pohlschroder M., Daniels C., Pfeiffer F., Allers T., Eisen J.A.;
RT "The complete genome sequence of Haloferax volcanii DS2, a model
RT archaeon.";
RL PLoS ONE 5:E9605-E9605(2010).
CC -!- FUNCTION: Involved in regulation of DNA replication.
CC {ECO:0000256|HAMAP-Rule:MF_01407}.
CC -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000256|HAMAP-
CC Rule:MF_01407}.
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DR EMBL; CP001957; ADE05207.1; -; Genomic_DNA.
DR RefSeq; WP_013035677.1; NC_013968.1.
DR AlphaFoldDB; D4H092; -.
DR EnsemblBacteria; ADE05207; ADE05207; HVO_C0001.
DR GeneID; 8926973; -.
DR KEGG; hvo:HVO_C0001; -.
DR HOGENOM; CLU_025112_3_1_2; -.
DR OrthoDB; 195574at2157; -.
DR Proteomes; UP000008243; Plasmid pHV1.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR014277; Orc1/Cdc6_arc.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR02928; orc1/cdc6 family replication initiation protein; 1.
DR PANTHER; PTHR10763; CELL DIVISION CONTROL PROTEIN 6-RELATED; 1.
DR PANTHER; PTHR10763:SF22; ORC1-TYPE DNA REPLICATION PROTEIN 3; 1.
DR Pfam; PF13191; AAA_16; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_01407}; DNA replication {ECO:0000256|HAMAP-Rule:MF_01407};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_01407}; Plasmid {ECO:0000313|EMBL:ADE05207.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008243}.
FT DOMAIN 52..211
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT BINDING 64..68
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT BINDING 210
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT BINDING 222
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
SQ SEQUENCE 408 AA; 45247 MW; 8B6431117D101215 CRC64;
MKLFNTDTET QVFRNRDSLQ DDYVPDELAG DTRDDEMQQL ATALQPIITG DQPDNVLVRG
PNGSGKTAAV RVVLNILDYE IESIEGVNFS YVIVNGSQHN TGYQLTRDLA NKLHPDTDFR
QGHSYSALLN AVAEGIKDLD GAVVVAIDEL SDIDDVDKLL YLLTRSSSND ALAGKQMGVV
ATTTDASFKN ELSPHVKSTI GKRTVKFDAY TSNQLREVLN HRVEKAFAEG SVDESAISLC
AALATQQGGD ARFALDLLKY GGDIANRGDG RVTETEINQA NDMWAREHVD SIVSDFSLKE
RQVLCAYMEL REVADVTSPR TAQIVRRYQT LAGRSKSAEV VSDRTVARYL QSLVDEGLLR
STLHQDKEGT WREYEPAFDS IHYLDALRSD VDRDKIAPHE DLVSMIKQ
//
