ID D4HT50_LEPIR Unreviewed; 354 AA.
AC D4HT50;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 28-JUN-2023, entry version 21.
DE SubName: Full=N-acetylneuraminic acid (Sialic acid) synthetase {ECO:0000313|EMBL:ADC94083.1};
GN Name=neuB {ECO:0000313|EMBL:ADC94083.1};
OS Leptospira interrogans serovar Hebdomadis.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=211881 {ECO:0000313|EMBL:ADC94083.1};
RN [1] {ECO:0000313|EMBL:ADC94083.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C401 {ECO:0000313|EMBL:ADC94083.1};
RA Cai C., Zhu Y., Zhong Y., Xin X., Jiang X.-G., He P., Qin J.-H.,
RA Zhao G.-P., Guo X.-K.;
RL Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADC94083.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C401 {ECO:0000313|EMBL:ADC94083.1};
RX PubMed=20196873; DOI=10.1186/1471-2180-10-67;
RA Cai C.S., Zhu Y.Z., Zhong Y., Xin X.F., Jiang X.G., Lou X.L., He P.,
RA Qin J.H., Zhao G.P., Wang S.Y., Guo X.K.;
RT "Development of O-antigen gene cluster-specific PCRs for rapid typing six
RT epidemic serogroups of Leptospira in China.";
RL BMC Microbiol. 10:67-67(2010).
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DR EMBL; FJ976889; ADC94083.1; -; Genomic_DNA.
DR AlphaFoldDB; D4HT50; -.
DR GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR CDD; cd11615; SAF_NeuB_like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.90.1210.10; Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain; 1.
DR InterPro; IPR006190; AFP_Neu5c_C.
DR InterPro; IPR036732; AFP_Neu5c_C_sf.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR013132; Neu5Ac_N.
DR InterPro; IPR013974; SAF.
DR PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR PANTHER; PTHR42966:SF1; SIALIC ACID SYNTHASE; 1.
DR Pfam; PF03102; NeuB; 1.
DR Pfam; PF08666; SAF; 1.
DR SMART; SM00858; SAF; 1.
DR SUPFAM; SSF51269; AFP III-like domain; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50844; AFP_LIKE; 1.
PE 4: Predicted;
FT DOMAIN 296..354
FT /note="AFP-like"
FT /evidence="ECO:0000259|PROSITE:PS50844"
SQ SEQUENCE 354 AA; 40042 MW; 50019AB796C0FAF5 CRC64;
MPQPIQLGNK IITGFFDPYV IAEIGVNHEG SIDIAKRLID EAKEGGADGA KFQTYKAETL
ASKNSPSYWD RTQEPTASQF ELFKKYDSFG WKEYEILAKH CQSVEIDFLS TPFDLEAVEH
LASQMPFIKV ASADITSVPL LRSVAKYSKP VILSTGSSTI PEIDFAMREL HANGASEIIL
LHCILNYPTK PENANLGMIQ DLQRIFPHHW IGYSDHTPPD LEMKSLIAAT LFGSVVLEKH
FTHDKTLPGN DHYHAMDKDD LKRFKRKLKE FESLIGSSEK APLQSEELSR KNARRSIVLS
KNLSKGSKIK EQDITFKRPA HGISPIFWDD VIGRVVNRNL LEDHILNWED LVQL
//
