ID D4JRV2_9FIRM Unreviewed; 560 AA.
AC D4JRV2;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Iron only hydrogenase large subunit, C-terminal domain {ECO:0000313|EMBL:CBK95821.1};
GN ORFNames=EUS_05270 {ECO:0000313|EMBL:CBK95821.1};
OS [Eubacterium] siraeum 70/3.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Oscillospiraceae incertae sedis.
OX NCBI_TaxID=657319 {ECO:0000313|EMBL:CBK95821.1, ECO:0000313|Proteomes:UP000008803};
RN [1] {ECO:0000313|EMBL:CBK95821.1, ECO:0000313|Proteomes:UP000008803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=70/3 {ECO:0000313|EMBL:CBK95821.1,
RC ECO:0000313|Proteomes:UP000008803};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT "The genome sequence of Eubacterium siraeum 70/3.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBK95821.1, ECO:0000313|Proteomes:UP000008803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=70/3 {ECO:0000313|EMBL:CBK95821.1,
RC ECO:0000313|Proteomes:UP000008803};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FP929044; CBK95821.1; -; Genomic_DNA.
DR AlphaFoldDB; D4JRV2; -.
DR KEGG; esu:EUS_05270; -.
DR PATRIC; fig|657319.3.peg.749; -.
DR HOGENOM; CLU_027268_0_0_9; -.
DR BioCyc; ESIR657319:G136K-447-MONOMER; -.
DR Proteomes; UP000008803; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 1.10.15.40; Electron transport complex subunit B, putative Fe-S cluster; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR007202; 4Fe-4S_dom.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR PANTHER; PTHR11615:SF368; HYDROGENASE-RELATED; 1.
DR PANTHER; PTHR11615; NITRATE, FORMATE, IRON DEHYDROGENASE; 1.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF13237; Fer4_10; 1.
DR Pfam; PF04060; FeS; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53920; Fe-only hydrogenase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS51656; 4FE4S; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 2..30
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 31..60
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 345..406
FT /note="4Fe-4S"
FT /evidence="ECO:0000259|PROSITE:PS51656"
SQ SEQUENCE 560 AA; 61976 MW; 6A034588C96CB002 CRC64;
MSYLRLKKSN CKNCYKCIRH CPVKSIRFSD GQANIVEDEC ILCGMCFVAC PQNAKQIRND
VGKAKELIVS GTPVYVSIAP SFVANYDGIG ITALNDALKK LGFAGAEETA EGAQLVTEQY
EKLVADGEHK IIISSCCHTV NTLIQKYYPQ ALPYLAQVKS PMLAHGEILK KKYPGCHTVF
IGPCLSKKAE ADAYAGAIDC VLTFEELTGW LKEENIEVCP VSDNAGRSNR AKTRLYPTTS
GILRSMNKDN PEYLYMAIDG VENCRNALRD IIDGNVGKCF IEMSACVNSC IGGPAMDKKH
EGVIHERRAV DEFAGSGRFD TVELADMTKS LPFISMQKTM PGSKAIEEIL RKMNKSDPSQ
ELNCGSCGYD TCREKAIAIL QGKADLTMCL PYLKEKAESF SDNIINNTPN GIMVLSEDLE
VQQINKAARE IMNIKSLSDV MGCPVVRILD PVSYLEVMST GENIHNKRTY LAEYGKYVEE
TIIYDKSYHI IMSIMRDITG EEISRAKREK NAAETIAVTD KVIEKQMRVV QEIASLLGET
TAETKVALTK LKENLSNDEQ
//
