ID D4JTI6_9FIRM Unreviewed; 256 AA.
AC D4JTI6;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Short-chain dehydrogenases of various substrate specificities {ECO:0000313|EMBL:CBK96405.1};
GN ORFNames=EUS_12400 {ECO:0000313|EMBL:CBK96405.1};
OS [Eubacterium] siraeum 70/3.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Oscillospiraceae incertae sedis.
OX NCBI_TaxID=657319 {ECO:0000313|EMBL:CBK96405.1, ECO:0000313|Proteomes:UP000008803};
RN [1] {ECO:0000313|EMBL:CBK96405.1, ECO:0000313|Proteomes:UP000008803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=70/3 {ECO:0000313|EMBL:CBK96405.1,
RC ECO:0000313|Proteomes:UP000008803};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT "The genome sequence of Eubacterium siraeum 70/3.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBK96405.1, ECO:0000313|Proteomes:UP000008803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=70/3 {ECO:0000313|EMBL:CBK96405.1,
RC ECO:0000313|Proteomes:UP000008803};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|ARBA:ARBA00006484, ECO:0000256|RuleBase:RU000363}.
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DR EMBL; FP929044; CBK96405.1; -; Genomic_DNA.
DR AlphaFoldDB; D4JTI6; -.
DR KEGG; esu:EUS_12400; -.
DR PATRIC; fig|657319.3.peg.1545; -.
DR HOGENOM; CLU_010194_2_1_9; -.
DR BioCyc; ESIR657319:G136K-1045-MONOMER; -.
DR Proteomes; UP000008803; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.
DR CDD; cd05233; SDR_c; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR42901; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR42901:SF1; ALCOHOL DEHYDROGENASE; 1.
DR Pfam; PF00106; adh_short; 1.
DR PIRSF; PIRSF000126; 11-beta-HSD1; 1.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023221};
KW Steroid metabolism {ECO:0000256|ARBA:ARBA00023221}.
SQ SEQUENCE 256 AA; 28153 MW; AE5D07BAD12A2D63 CRC64;
MIALITGASS GIGKEMAKNL ATRGVNLILV ARRTERLLAL KEEIVYNCPE IKVKTITADL
SKEDQCFELY DRVKEYKIDF LFNNAGFGLY GPFLETDLKD ELSMINVNIK AVHILTKLFL
RDFAARNSGY ILNTASVAGF MAGPLLATYY ATKNYVVQLT KAVYEELRST GSRVVISALC
PGPVDTEFNS VAGVKSFGIP SENEAYVADY AIERLLCGDL LIIPGVTTKA AAAGSRFAPT
KFLLRTVRTL QEQKNK
//
