ID   D4K3Y8_9FIRM            Unreviewed;       467 AA.
AC   D4K3Y8;
DT   18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT   18-MAY-2010, sequence version 1.
DT   24-JAN-2024, entry version 54.
DE   SubName: Full=Pyruvate/oxaloacetate carboxyltransferase {ECO:0000313|EMBL:CBK98231.1};
DE            EC=4.1.1.3 {ECO:0000313|EMBL:CBK98231.1};
GN   ORFNames=FP2_06020 {ECO:0000313|EMBL:CBK98231.1};
OS   Faecalibacterium prausnitzii L2-6.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Faecalibacterium.
OX   NCBI_TaxID=718252 {ECO:0000313|EMBL:CBK98231.1, ECO:0000313|Proteomes:UP000008804};
RN   [1] {ECO:0000313|EMBL:CBK98231.1, ECO:0000313|Proteomes:UP000008804}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L2-6 {ECO:0000313|Proteomes:UP000008804};
RG   metaHIT consortium -- http://www.metahit.eu/;
RA   Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT   "The genome sequence of Faecalibacterium prausnitzii L2/6.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CBK98231.1, ECO:0000313|Proteomes:UP000008804}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L2-6 {ECO:0000313|Proteomes:UP000008804};
RA   Pajon A.;
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FP929045; CBK98231.1; -; Genomic_DNA.
DR   AlphaFoldDB; D4K3Y8; -.
DR   STRING; 718252.FP2_06020; -.
DR   KEGG; fpr:FP2_06020; -.
DR   PATRIC; fig|718252.3.peg.1814; -.
DR   eggNOG; COG5016; Bacteria.
DR   HOGENOM; CLU_000395_4_2_9; -.
DR   BioCyc; FPRA718252:G1375-508-MONOMER; -.
DR   Proteomes; UP000008804; Chromosome.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   CDD; cd07937; DRE_TIM_PC_TC_5S; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR003379; Carboxylase_cons_dom.
DR   InterPro; IPR000891; PYR_CT.
DR   PANTHER; PTHR45266; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR   PANTHER; PTHR45266:SF3; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR   Pfam; PF00682; HMGL-like; 1.
DR   Pfam; PF02436; PYC_OADA; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   SUPFAM; SSF89000; post-HMGL domain-like; 1.
DR   PROSITE; PS50991; PYR_CT; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:CBK98231.1};
KW   Pyruvate {ECO:0000313|EMBL:CBK98231.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008804};
KW   Transferase {ECO:0000313|EMBL:CBK98231.1}.
FT   DOMAIN          6..266
FT                   /note="Pyruvate carboxyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS50991"
SQ   SEQUENCE   467 AA;  51946 MW;  2B9FC9A9EBE84E14 CRC64;
     MAKKPIKITE VVLRDAHQSL LATRMTMDEM RPILPEMDKI PYFSVECWGG ATFDSCIRFL
     DEDPWERLRI LRKELPHQKL QMLFRGQNML GYRPYADDAV EYFVKKSVAN GIDVIRIFDA
     LNDARNLQTA IKSANKEGAH VQGCISYTLS PVHNNEYYVK YAKTLEEMGA NSICIKDMAG
     LLTPYTCYEL VKELKNTLSI PVDIHSHYTA GLASMSLLKG IEAGADIVDT AMSPLSGGTS
     HMATESLVAA LQGTDYDTGL DLKQLNVVRA YFAKLREKYI ANGQISPKSL GVDANTLLYQ
     VPGGMFSNML KQLKDAGKED KLDEVLAEIP RVREDAGYPP LVTPTSQIVG TQAVFNVILG
     ERYKMVTKEF KGLVHGDYGK TPAPISAEFT KKILGDEKPI TCRFADTLAP EMDKLKAEAA
     KWAIQEEDVL TYAMFPQVAP KFFEKRNAKA QGVDADHADF ANKSHPV
//