ID D4LC15_RUMC1 Unreviewed; 770 AA.
AC D4LC15;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Acyl-coenzyme A synthetases/AMP-(Fatty) acid ligases {ECO:0000313|EMBL:CBL17160.1};
GN OrderedLocusNames=RUM_09930 {ECO:0000313|EMBL:CBL17160.1};
OS Ruminococcus champanellensis (strain DSM 18848 / JCM 17042 / KCTC 15320 /
OS 18P13).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=213810 {ECO:0000313|EMBL:CBL17160.1, ECO:0000313|Proteomes:UP000007054};
RN [1] {ECO:0000313|Proteomes:UP000007054}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18848 / JCM 17042 / 18P13
RC {ECO:0000313|Proteomes:UP000007054};
RA Pajon A., Turner K., Parkhill J., Bernalier A.;
RT "The genome sequence of Ruminococcus sp. 18P13.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; FP929052; CBL17160.1; -; Genomic_DNA.
DR AlphaFoldDB; D4LC15; -.
DR STRING; 213810.RUM_09930; -.
DR KEGG; rch:RUM_09930; -.
DR PATRIC; fig|213810.4.peg.895; -.
DR HOGENOM; CLU_000022_59_10_9; -.
DR Proteomes; UP000007054; Chromosome.
DR GO; GO:0016878; F:acid-thiol ligase activity; IEA:UniProt.
DR GO; GO:0016405; F:CoA-ligase activity; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR CDD; cd02209; cupin_XRE_C; 1.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR013096; Cupin_2.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR011051; RmlC_Cupin_sf.
DR PANTHER; PTHR43605:SF10; ACYL-COA SYNTHETASE MEDIUM CHAIN FAMILY MEMBER 3; 1.
DR PANTHER; PTHR43605; ACYL-COENZYME A SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF07883; Cupin_2; 1.
DR Pfam; PF01381; HTH_3; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF51182; RmlC-like cupins; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:CBL17160.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007054}.
FT DOMAIN 16..70
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 770 AA; 86526 MW; DAEFEEDE14710166 CRC64;
MGANMDHAIK EVAERIRAVR EDVGLSVEEM AKRTDVSVEE YKALEAGQSD FSFTFIYKCA
KACGVEITDV MEGESPKVTS YTVTRAGKGL PIVRREGFAY YRLAPQFRHK ISEPFFVKIP
YSEEAMDKPL HMASHEGQEF DIVVKGCMKI YIGDHSEILH PGDSIYYDSS TPHDEVAIGG
EDCEIYAIVM NPNGQGGVPE YKEHVQTRVL TNVDKAGLVH PVAEKFVSTT TDEFGHLTGI
EYHNTDTFNF GFDIVDKVAE KTPDKLAMLH VSNDFTERRF TFADMKHYSN MTANYFRSLG
IKKGDRVMLV LKRHYQFWFS IVALHKLGAI AIPATNQLLE HDYVYRFDAA GVSAIVCTGD
GDVTTHVEGA VKQCKSVKTL ICTGGPRPGW HDFDGELPAY SDKFERTEDT SCGDDPILMF
FTSGTTGYPK IATHSHKYGL GHFLTAKYWQ NVDPNGLHFT ISDTGWGKAL WGKLYGQWMN
EAPVFTYDFD RFDANKILPM FAKYHITTFC APPTMFRFFI KEDLSKFDLS SLKYAVVAGE
ALNPEVYNRF LEATGIKLME GFGQTETTLS IANFVGDSNK VGSMGRPSPL YDIDIVLPDG
TPAKPGETGE IVIRTDKKVP CGLYLGYYNN EEKTKEAWHD GAYHTGDTAW RDEDGYFWYV
GRVDDLIKSS GYRIGPFEIE SVIMELPYVL ECAITAAPDE IRGQVVKASI VLTKGTEASE
ALKKEIQNYV KEHTAPYKYP RIVEFMEELP KTISGKIRRV ALRESSEKQK
//
