ID   D4LDL4_RUMC1            Unreviewed;       453 AA.
AC   D4LDL4;
DT   18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT   18-MAY-2010, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=Permeases {ECO:0000313|EMBL:CBL17709.1};
GN   OrderedLocusNames=RUM_16240 {ECO:0000313|EMBL:CBL17709.1};
OS   Ruminococcus champanellensis (strain DSM 18848 / JCM 17042 / KCTC 15320 /
OS   18P13).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Ruminococcus.
OX   NCBI_TaxID=213810 {ECO:0000313|EMBL:CBL17709.1, ECO:0000313|Proteomes:UP000007054};
RN   [1] {ECO:0000313|Proteomes:UP000007054}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18848 / JCM 17042 / 18P13
RC   {ECO:0000313|Proteomes:UP000007054};
RA   Pajon A., Turner K., Parkhill J., Bernalier A.;
RT   "The genome sequence of Ruminococcus sp. 18P13.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|PIRNR:PIRNR005353};
CC       Multi-pass membrane protein {ECO:0000256|PIRNR:PIRNR005353}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697,
CC       ECO:0000256|PIRNR:PIRNR005353}.
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DR   EMBL; FP929052; CBL17709.1; -; Genomic_DNA.
DR   RefSeq; WP_015558615.1; NZ_BBEP01000001.1.
DR   AlphaFoldDB; D4LDL4; -.
DR   STRING; 213810.RUM_16240; -.
DR   GeneID; 83156337; -.
DR   KEGG; rch:RUM_16240; -.
DR   PATRIC; fig|213810.4.peg.1523; -.
DR   HOGENOM; CLU_024508_0_1_9; -.
DR   OrthoDB; 9808458at2; -.
DR   BioCyc; RCHA213810:RUM_RS07905-MONOMER; -.
DR   Proteomes; UP000007054; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR   InterPro; IPR045018; Azg-like.
DR   InterPro; IPR026033; Azg-like_bact_archaea.
DR   InterPro; IPR006043; NCS2.
DR   PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR   PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PIRSF; PIRSF005353; PbuG; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR005353};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007054};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005353}.
FT   TRANSMEM        20..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        51..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        95..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        134..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        172..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        199..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        259..284
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        347..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        396..423
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        435..452
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   453 AA;  48145 MW;  AA18933D1C3F7E75 CRC64;
     MFEKLFKLQA NKTNVKTELA AGLTTFMTMA YILAVNPSIL SSTGMDSTAV LLATCLASFV
     GTICMALWAN LPFALSAGMG LNAYMAYTVC GTMGFSWQVA LFAVFIEGII FIILSLTNVR
     EAIFNSIPLP LKRAVSVGIG LFIAFIGLQN AGLSVDASTL VTITDFTQNF HTTGICALLA
     VIGLLLTSVL YIKKVKGSIL IGILGTWILG MLCQLTGLYV PNPDAGAYTL FPTLGITDFT
     KLSQTFGQCF KLDFGNVGIL NFVVVIFSFL FVDLFDTLGT LIGVSTKANM LDKDGKLPAI
     KPALLADAVA TSAGAVFGTS TTTTFVESSA GVAAGGRTGL TALTTAVLFL ISMLFAPIFT
     AIPSFATAPA LILVGFLMFS TVTEIKLTED TYTSAIPAYL CIIAMPLFYS ISEGISIGVI
     SYVIINLICG KRKEINPIMY VLAVLFILKY IFL
//