UniProt: D4M3K8

Database: UniProt
Entry: D4M3K8_9FIRM

LinkDB:  D4M3K8_9FIRM 
Original site:  D4M3K8_9FIRM

All links

Ontology (5)   
   GO (5)   
Gene (1)   
   KEGG GENES (1)   
DNA sequence (1)   
   EMBL (1)   
Protein domain (21)   
   InterPro (13)   
   Pfam (4)   
   PROSITE (3)   
   SMART (1)   
All databases (28)   

Download RDF

ID   D4M3K8_9FIRM            Unreviewed;      2557 AA.
AC   D4M3K8;
DT   18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT   18-MAY-2010, sequence version 1.
DT   27-MAR-2024, entry version 75.
DE   SubName: Full=Amino acid adenylation domain {ECO:0000313|EMBL:CBL25820.1};
GN   ORFNames=RTO_11540 {ECO:0000313|EMBL:CBL25820.1};
OS   [Ruminococcus] torques L2-14.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Mediterraneibacter.
OX   NCBI_TaxID=657313 {ECO:0000313|EMBL:CBL25820.1, ECO:0000313|Proteomes:UP000008956};
RN   [1] {ECO:0000313|EMBL:CBL25820.1, ECO:0000313|Proteomes:UP000008956}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L2-14 {ECO:0000313|EMBL:CBL25820.1,
RC   ECO:0000313|Proteomes:UP000008956};
RG   metaHIT consortium -- http://www.metahit.eu/;
RA   Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT   "The genome sequence of Ruminococcus torques L2-14.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CBL25820.1, ECO:0000313|Proteomes:UP000008956}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L2-14 {ECO:0000313|EMBL:CBL25820.1,
RC   ECO:0000313|Proteomes:UP000008956};
RA   Pajon A.;
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC         Evidence={ECO:0000256|ARBA:ARBA00001957};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FP929055; CBL25820.1; -; Genomic_DNA.
DR   KEGG; rto:RTO_11540; -.
DR   PATRIC; fig|657313.3.peg.933; -.
DR   HOGENOM; CLU_000022_40_1_9; -.
DR   Proteomes; UP000008956; Chromosome.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009403; P:toxin biosynthetic process; IEA:UniProt.
DR   CDD; cd12114; A_NRPS_TlmIV_like; 1.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   CDD; cd19535; Cyc_NRPS; 2.
DR   Gene3D; 3.30.300.30; -; 3.
DR   Gene3D; 1.10.1200.10; ACP-like; 3.
DR   Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 2.
DR   Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR001242; Condensatn.
DR   InterPro; IPR013217; Methyltransf_12.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR006162; Ppantetheine_attach_site.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   NCBIfam; TIGR01733; AA-adenyl-dom; 2.
DR   PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR   PANTHER; PTHR45527:SF10; PHENYLOXAZOLINE SYNTHASE MBTB; 1.
DR   Pfam; PF00501; AMP-binding; 2.
DR   Pfam; PF00668; Condensation; 2.
DR   Pfam; PF08242; Methyltransf_12; 1.
DR   Pfam; PF00550; PP-binding; 3.
DR   SMART; SM00823; PKS_PP; 2.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR   SUPFAM; SSF47336; ACP-like; 3.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS00455; AMP_BINDING; 2.
DR   PROSITE; PS50075; CARRIER; 3.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 2.
PE   4: Predicted;
KW   Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          1..72
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
FT   DOMAIN          1423..1498
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
FT   DOMAIN          2482..2557
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
SQ   SEQUENCE   2557 AA;  292832 MW;  91FA9464CAEE79F1 CRC64;
     MEYIEIKEQI KQKLPVARDL GDSENLLELG LSSLTIMRLV NQWRKQGVKV SFGSLMENPT
     LEGWWALIQR SMKKKAGKKR AQESKITPEK DMKQPFPLTD VQYAYWVGRD EEQALGGIDC
     HAYLEFDGGN IDPERLEKAW NVLQYHHPML RACFLEDGTQ KILDKPYCEK IKVHDFSRMP
     SEEAEAMAVS VRERLSHRKL KIEEGEVAGI ELTLFPENRA RMHVDMALLV ADVQSLQILL
     RDLAAAYRGE SLPAESKGWN FASYLERQKE EDKEERNNAE GYWKKRLEHL PKGPGLPLAK
     RPQEVTKTVF NRRIVRIGKE EWAHLQVRAK EYQTTPAMVL LTAYATVLER WSRNHRFLIN
     IPFFNRKTEQ QGLEDVIADF TTLLLLEIDC EGNPTFAELL DRIQKQLHED MKYTAYSGVQ
     VQRDLAQMYG DASAVAPVVF ACNLGTPLVN DMFRKELGQF SYMISQTPQV WNDFQSYEDE
     NGVQLTWDSV DKLFPENMIP DMLECFENLL HELGKKDWNQ RFDVLPEKRK REIEDTARTG
     VPERVECLHW AVMNHAEVCP EDIALIDAGS GRSVSYGELK ARATAVAAGI SEKDIKGVPV
     ALTLPRGIEQ IEAALGILLS GNSYLPVSLS QPKDRRALIH EKTGVRYVVT NRELSEKLDW
     PEGTEILVME GMEERQENVR LPEVSPKDSA YIIMTSGSTG VPKGVEIAHE SAWNTVQDIN
     EKYHVTSADR ALAVSAMDFD LSVYDVFGIL GAGGTLVLLP EQERRNADYW LEQVLKYQIT
     VWNSVPVLLD MLLIRAESMK QKLPIRAVML SGDWIGMDLP QRVAAWTEDC QFVAMGGATE
     ASIWSNYQNV TLPMPKNWKS IPYGKPLRYQ AYRVVDEYGR DCPYWAEGEL WIGGFGVAKG
     YRGDSALTGQ KFITDQYGRW YRTGDLGRIW DDETIEFLGR KDHQVKIRGH RIELGEIEHA
     IQEFPGVAHA VVDTVSDGHG NKTLAAYIGA PIQEDSKVTT YLYGTDIFGG GWKELKDDVS
     NWQMQQERKT AYKNFLAYAD QRCVQLMLET LIELGIFVSE KEVLSQKEIF EKGSITETQK
     NTVARWLEIL KKEGILREED GRLSRTGKEV AVPEKAGDTE TYFNKLKPYL KHMVTGNEVP
     LDVFYQKEPA LAPNMLLRRI PGCEETVERL VQGLRLLAEE RRKEPLQIIE IGTRDTAITR
     QFLNALEDVS VAYTYADSSK YFLQEAEKEL AGYERVEFEM LNLEEGMDKQ QMSLHSYDVV
     ISVNALHRNI DAADAVKKVA ELLKPNGILL MTDLVVRTYL QELTAAFLEN GFADIRDKRK
     EAGLVTPDCL LWRECLSEAG LGEDCAVTER YGRCICCSRQ QASVLSYHNG ALREYLSEKL
     PEYMVPQNYH FMEQLPTLSN GKINRKQLRE DFKEETAVIR FSKATTETEE KLLDIWKQLF
     GYENIGIEDN YFSLGGDSLI ATRLISEVQK TFGCKITIST IFENLTVKSL AKAIEQSEQK
     EEDTLQIKPN LEEAYHPFPL TDVQYAYWLG RSGLYELGNV ATHCYFELDA DGLDTECAET
     AWNLLIQRHG MMRVIIQPDG MQRILENTPQ YHIDVTDIRQ LEVTEKEKAL DEKRAEMSHQ
     VIQTDEWPLF DVRITKIEDQ KHRIHISFDN IIFDGWSMFH LLNEWAEVYR NGKAEMPITL
     SFRDYVLGLE QIKSTSAYEK DKKYWEDRVE TFADAPDLPL AKNESQITEQ RFCRRSAKLS
     QKEWQSVKDA AGRLEVTPSV LLMSAYAETL RLWSSNKDFT LNLTQFDRKQ LHPEVNNLVG
     DFTTLTLLEI KNAGNNFAER TKAIQKQLTE DLEHTAYGAV ELERELKKKT GNMRGAIMPV
     VFTSGLGVEQ WNEGKWLGKL NYNISQTPQV WLDHQVVEMD GCLCLFWDSV DELFYPGMLD
     EMFRAYTGLL HTLAVHPEIM QEKTASLVTA EISEKRRQAN ETAAEFEEKT LDGLFLEAAD
     KFPDKEALVT CSRRMTYREI KEEAFYISGQ LKSMGIKKEE TVAVFMEKGW EQVVAVYGIL
     FAGAAYLPID IHNPRERVEK ILRDSGTRII LVQNQAYDQD TEWLHEWDCI SVSGLKTDSE
     YKAQENKAGD LAYVIYTSGT TGMPKGVMIT HHNAVNTILD INARYQITEQ DTAFGISNLH
     FDLSVYDVFG VLGAGGKLVL PDPEYGKDPA HWIHWLNHEN ITVWNSVPAF VEMLAEYEEY
     QRQVTSQSLR LVMMSGDWVP VSLPGRIRNL FQNVEIVALG GATEGSIWSN HFEIPEIVPE
     DWKSIPYGKP LANQKYYVLD QNMEDCPDWV PGTLYIAGDG VAQGYLNDNE KTEEKFVVLD
     RTGERLYCTG DMGRYWNEGN IEFLGRLDNQ VKINGYRVEL GEIEAALRRI QGITEAFVFF
     KRDNAIEDIC AVLVEEKRYR DRIDKFYKEM LKKDLPIYMI PTEYIKTNAI PLNSNGKKDI
     HKILIVAEKN RKPIFKKNNN CKQLTQLQEQ LLAIWREVLK IENIDINDNF FEIGGNSIQA
     IQITNQMTEK IGCFMDIGKL FEYPTISKIE RYILEET
//

DBGET integrated database retrieval system