ID D4TXZ4_9ACTO Unreviewed; 358 AA.
AC D4TXZ4;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Putative 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase {ECO:0000313|EMBL:EFF80228.1};
DE Flags: Fragment;
GN ORFNames=HMPREF0970_00817 {ECO:0000313|EMBL:EFF80228.1};
OS Schaalia odontolytica F0309.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Schaalia.
OX NCBI_TaxID=649742 {ECO:0000313|EMBL:EFF80228.1, ECO:0000313|Proteomes:UP000003150};
RN [1] {ECO:0000313|EMBL:EFF80228.1, ECO:0000313|Proteomes:UP000003150}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0309 {ECO:0000313|EMBL:EFF80228.1,
RC ECO:0000313|Proteomes:UP000003150};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the vitamin-B12 independent methionine synthase
CC family. {ECO:0000256|ARBA:ARBA00009553}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFF80228.1}.
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DR EMBL; ACYT02000020; EFF80228.1; -; Genomic_DNA.
DR AlphaFoldDB; D4TXZ4; -.
DR PATRIC; fig|649742.3.peg.551; -.
DR HOGENOM; CLU_772757_0_0_11; -.
DR OrthoDB; 244285at2; -.
DR Proteomes; UP000003150; Unassembled WGS sequence.
DR GO; GO:0003871; F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd03311; CIMS_C_terminal_like; 1.
DR Gene3D; 3.20.20.210; -; 1.
DR InterPro; IPR002629; Met_Synth_C/arc.
DR InterPro; IPR038071; UROD/MetE-like_sf.
DR PANTHER; PTHR30519; 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE; 1.
DR PANTHER; PTHR30519:SF0; 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE; 1.
DR Pfam; PF01717; Meth_synt_2; 1.
DR SUPFAM; SSF51726; UROD/MetE-like; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000313|EMBL:EFF80228.1};
KW Transferase {ECO:0000313|EMBL:EFF80228.1};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 26..348
FT /note="Cobalamin-independent methionine synthase MetE C-
FT terminal/archaeal"
FT /evidence="ECO:0000259|Pfam:PF01717"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EFF80228.1"
SQ SEQUENCE 358 AA; 39087 MW; 24DC103EC1CA1F05 CRC64;
TDADRAREPY LEREAAQTER LHLPPLPTTT IGSFPQTTEI RKARAANARG ELSDADYEAR
MREEIASVIT LQEELGLDML VHGEAERNDM VQYFAELLDG FAATRNGWVQ SYGSRCTRPS
VLWGDVSRPA PMTVGWTSYA QSLTDKPVKG MLTGPVTIIA WSFPRNDLPL GEIADQIGLA
LRDEVSDLEA AGIAAIQVDE PALRELLPLD ADCHADYLNW SVGSFRLATS SVRPDTQIHT
HLCYSEFGQI IDAIKGLDAD VTSIEAARSK MEVVPELAEA GFDHGIGPGV WDIHAPRVPG
TEELAELIGL AADAVPVSRL WVNPDCGLKT RGYVETKASL DNLVSATRQV RAQRGLES
//
