ID D5ARR1_RHOCB Unreviewed; 458 AA.
AC D5ARR1;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=D-2-hydroxyglutarate dehydrogenase {ECO:0000313|EMBL:ADE84932.1};
DE EC=1.1.99.- {ECO:0000313|EMBL:ADE84932.1};
GN OrderedLocusNames=RCAP_rcc01174 {ECO:0000313|EMBL:ADE84932.1};
OS Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Rhodobacter.
OX NCBI_TaxID=272942 {ECO:0000313|EMBL:ADE84932.1, ECO:0000313|Proteomes:UP000002361};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SB1003;
RA Strnad H., Lapidus A., Vlcek C., Ulbrich P., Paces J., Maltsev N.,
RA Kumar V., Kogan Y., Milgram A., Rebrekov D., Mazur M., Cox R., Kyrpides N.,
RA Kolar M., Sachova J., Ridl J., Ivanova N., Kapatral V., Los T., Lykidis A.,
RA Mikhailova N., Reznik G., Vasieva O., Fonstein M., Paces V., Haselkorn R.;
RT "Complete genome sequence of Rhodobacter capsulatus SB1003.";
RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADE84932.1, ECO:0000313|Proteomes:UP000002361}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-309 / NBRC 16581 / SB1003
RC {ECO:0000313|Proteomes:UP000002361};
RX PubMed=20418398; DOI=10.1128/JB.00366-10;
RA Strnad H., Lapidus A., Paces J., Ulbrich P., Vlcek C., Paces V.,
RA Haselkorn R.;
RT "Complete genome sequence of the photosynthetic purple nonsulfur bacterium
RT Rhodobacter capsulatus SB 1003.";
RL J. Bacteriol. 192:3545-3546(2010).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the FAD-binding oxidoreductase/transferase type
CC 4 family. {ECO:0000256|ARBA:ARBA00008000}.
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DR EMBL; CP001312; ADE84932.1; -; Genomic_DNA.
DR RefSeq; WP_013066911.1; NC_014034.1.
DR AlphaFoldDB; D5ARR1; -.
DR STRING; 272942.RCAP_rcc01174; -.
DR GeneID; 31490086; -.
DR KEGG; rcp:RCAP_rcc01174; -.
DR eggNOG; COG0277; Bacteria.
DR HOGENOM; CLU_017779_4_1_5; -.
DR OrthoDB; 9811557at2; -.
DR Proteomes; UP000002361; Chromosome.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008152; P:metabolic process; IEA:UniProt.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.30.70.2190; -; 1.
DR Gene3D; 3.30.70.2740; -; 1.
DR Gene3D; 3.30.43.10; Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2; 1.
DR InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016167; FAD-bd_PCMH_sub1.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR InterPro; IPR006094; Oxid_FAD_bind_N.
DR InterPro; IPR016171; Vanillyl_alc_oxidase_C-sub2.
DR PANTHER; PTHR43716; D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43716:SF1; D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF02913; FAD-oxidase_C; 1.
DR Pfam; PF01565; FAD_binding_4; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022827};
KW Oxidoreductase {ECO:0000313|EMBL:ADE84932.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002361}.
FT DOMAIN 33..211
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
SQ SEQUENCE 458 AA; 47631 MW; 886ACBF3A2523000 CRC64;
MDLLDRLSDL LGPAQVLRGA EALAYGREWT GHYVWEPLAV VRPGTTEEVA AVLRLAHQTG
TPVVPLGGNT GLNGGTFAPG ALMLSLSRMN RIRDLNPAAR TVVAEAGVVL ETLQDLAAAQ
GLAFPLSFGA KGSAMVGGFL STNAGGSNVL RYGSARALCL GLEVVLADGR IWHGLTGLHK
DNTGYDLRDL IIGAEGTLGV ITAAVLKLVP APGAYATALV GLDSLSEALA LLNTVQSGTG
GAVEAFEFMP DRYMARLSRL KPALACPYAP RPVNLLIETA TTVPGADPGA ALEALLGAAM
EAGQIAEAVI AQSASQRRKL WEMRESAAEI TFTTPDIVDC DIALPLDRLE NFLARMTPAL
AELDPGAEEL VIAHLGDGNI HYTAYPSRPD PVLAQAIRAR VSTEAVALGG SFSAEHGVGI
SKRATMAAHK DPVALQMMAA IKAALDPKGI LNPGKVLP
//
