ID D5E4U3_MYCCM Unreviewed; 457 AA.
AC D5E4U3;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Cytosol leucyl aminopeptidase {ECO:0000313|EMBL:ADE19827.1};
DE EC=3.4.11.1 {ECO:0000313|EMBL:ADE19827.1};
GN Name=pepB {ECO:0000313|EMBL:ADE19827.1};
GN OrderedLocusNames=MCRO_0111 {ECO:0000313|EMBL:ADE19827.1};
OS Mycoplasma crocodyli (strain ATCC 51981 / MP145).
OC Bacteria; Mycoplasmatota; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=512564 {ECO:0000313|EMBL:ADE19827.1, ECO:0000313|Proteomes:UP000001845};
RN [1] {ECO:0000313|Proteomes:UP000001845}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51981 / MP145 {ECO:0000313|Proteomes:UP000001845};
RA Glass J.I., Durkin A.S., Hostetler J., Jackson J., Johnson J., May M.A.,
RA Paralanov V., Radune D., Szczypinski B., Brown D.R.;
RT "The complete genome of Mycoplasma crocodyli MP145.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MP145;
RA Ma Z., Wang X., Liu H.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ADE19827.1, ECO:0000313|Proteomes:UP000001845}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51981 / MP145 {ECO:0000313|Proteomes:UP000001845};
RX PubMed=21460083; DOI=10.1128/JB.00309-11;
RA Brown D.R., Farmerie W.G., May M., Benders G.A., Durkin A.S., Hlavinka K.,
RA Hostetler J., Jackson J., Johnson J., Miller R.H., Paralanov V., Radune D.,
RA Szczypinski B., Glass J.I.;
RT "Genome sequences of Mycoplasma alligatoris A21JP2T and Mycoplasma
RT crocodyli MP145T.";
RL J. Bacteriol. 193:2892-2893(2011).
CC -!- SIMILARITY: Belongs to the peptidase M17 family.
CC {ECO:0000256|ARBA:ARBA00009528}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001991; ADE19827.1; -; Genomic_DNA.
DR RefSeq; WP_013054603.1; NC_014014.1.
DR AlphaFoldDB; D5E4U3; -.
DR STRING; 512564.MCRO_0111; -.
DR KEGG; mcd:MCRO_0111; -.
DR eggNOG; COG0260; Bacteria.
DR HOGENOM; CLU_013734_6_3_14; -.
DR OrthoDB; 9809354at2; -.
DR Proteomes; UP000001845; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00433; Peptidase_M17; 1.
DR Gene3D; 3.40.220.10; Leucine Aminopeptidase, subunit E, domain 1; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR011356; Leucine_aapep/pepB.
DR InterPro; IPR043472; Macro_dom-like.
DR InterPro; IPR000819; Peptidase_M17_C.
DR PANTHER; PTHR11963; LEUCINE AMINOPEPTIDASE-RELATED; 1.
DR PANTHER; PTHR11963:SF23; ZGC:152830; 1.
DR Pfam; PF00883; Peptidase_M17; 1.
DR PRINTS; PR00481; LAMNOPPTDASE.
DR SUPFAM; SSF52949; Macro domain-like; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS00631; CYTOSOL_AP; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000256|ARBA:ARBA00022438,
KW ECO:0000313|EMBL:ADE19827.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ADE19827.1};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000001845}.
FT DOMAIN 309..316
FT /note="Cytosol aminopeptidase"
FT /evidence="ECO:0000259|PROSITE:PS00631"
SQ SEQUENCE 457 AA; 50410 MW; 8B70D69BE04E07C0 CRC64;
MITKITNTRN SSQLLKAVFK KDAYPKTLLE KKFSVTDYFD TKESLVFMGD KKEYKLEDAI
SFAKTISKSA QRDYQIDLDS FVAGDVTIQQ LVKFFVESYN YTSYKLWNLK TKKDEPKFEI
TLFSSVNETE YKEALTEALI LSESLNFARE LQIMAPNVCN SEYLADVVAK EVKKHKNLTL
KVLNKKEIED HKMGLLLSVN KGSVYEPRVV VIEYTGNPAS KEKTVLVGKG ITFDSGGYSL
KPSKSMLGMK FDMSGSVIVA STLLAIAQLK PKANFSAVLC ITDNRVNGDA SLPDSVWVSM
NGKSVEINNT DAEGRLVMAD GLTYAVRKLN ATRLIDVATL TGAILVALGS TYTGAWSTTE
KGWQELSMAA NTQNELIWRM PLDEAFAKEI RNSYVADLKN TDLSGNGGGS SSAAMFLKEF
TEGVEYIHLD VAGTADLGGQ PTGVMIKTLT QMALNNK
//
