ID D5E9P4_METMS Unreviewed; 442 AA.
AC D5E9P4;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Phosphomethylpyrimidine kinase {ECO:0000313|EMBL:ADE35895.1};
GN OrderedLocusNames=Mmah_0363 {ECO:0000313|EMBL:ADE35895.1};
OS Methanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanohalophilus.
OX NCBI_TaxID=547558 {ECO:0000313|EMBL:ADE35895.1, ECO:0000313|Proteomes:UP000001059};
RN [1] {ECO:0000313|EMBL:ADE35895.1, ECO:0000313|Proteomes:UP000001059}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35705 / DSM 5219 / SLP
RC {ECO:0000313|Proteomes:UP000001059};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Lykidis A., Saunders E., Brettin T., Detter J.C., Han C., Land M.,
RA Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D.,
RA Spring S., Schneider S., Schroeder M., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Methanohalophilus mahii DSM 5219.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001994; ADE35895.1; -; Genomic_DNA.
DR RefSeq; WP_013036838.1; NC_014002.1.
DR AlphaFoldDB; D5E9P4; -.
DR STRING; 547558.Mmah_0363; -.
DR GeneID; 8982497; -.
DR KEGG; mmh:Mmah_0363; -.
DR HOGENOM; CLU_035788_0_0_2; -.
DR OrthoDB; 43786at2157; -.
DR Proteomes; UP000001059; Chromosome.
DR GO; GO:0008972; F:phosphomethylpyrimidine kinase activity; IEA:InterPro.
DR GO; GO:0004789; F:thiamine-phosphate diphosphorylase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR CDD; cd01169; HMPP_kinase; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR Gene3D; 3.40.225.10; Class II aldolase/adducin N-terminal domain; 1.
DR InterPro; IPR036409; Aldolase_II/adducin_N_sf.
DR InterPro; IPR004399; HMP/HMP-P_kinase_dom.
DR InterPro; IPR013749; PM/HMP-P_kinase-1.
DR InterPro; IPR029056; Ribokinase-like.
DR InterPro; IPR019293; ThiN.
DR NCBIfam; TIGR00097; HMP-P_kinase; 1.
DR PANTHER; PTHR20858:SF17; HYDROXYMETHYLPYRIMIDINE_PHOSPHOMETHYLPYRIMIDINE KINASE THI20-RELATED; 1.
DR PANTHER; PTHR20858; PHOSPHOMETHYLPYRIMIDINE KINASE; 1.
DR Pfam; PF08543; Phos_pyr_kin; 1.
DR Pfam; PF10120; ThiP_synth; 1.
DR SUPFAM; SSF53639; AraD/HMP-PK domain-like; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ADE35895.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001059};
KW Transferase {ECO:0000313|EMBL:ADE35895.1}.
FT DOMAIN 14..255
FT /note="Pyridoxamine kinase/Phosphomethylpyrimidine kinase"
FT /evidence="ECO:0000259|Pfam:PF08543"
SQ SEQUENCE 442 AA; 46780 MW; 415DCC2788251600 CRC64;
MSNTKVALTI AGSDSGGGAG IEADIRTFSA LGMHPTCAVT CITSQNTMGL QDSMEVPISH
ISSQIDAVCT DMDVKWAKTG MLSSPEIIAA VASEVKKHRL KLVVDPVMTA EAGGTLLAES
ALSTLKETLL PLAFVVTPNI YEAKALSGVT INTWEDGQKA ARRIAKFGVD NVIITGGHFD
ASDLVYESHN DTFTTISSRF VKGGTHGSGC TYSAALLVYL SNGLRVPEAS RCAKRFVENA
ISRSTDVGMG VSPVDSLAFL RNSAAKYHTL VNTTDALDTL ISEKTFSKLI PEVGCNIAMA
TPEAETISDV AGVHGRITRS KGRPVASGCV GFGASKHVGS VVLAAIHSNP EIRACLNVKY
SKEVLAACSQ MGFGIASFER KDEPSHVSTM DWGTAYAIGK YGKVPEVIYD EGDVGKEPMI
RLLGRNATDV VEMALKIVER IN
//
