ID D5KB36_9ROSA Unreviewed; 136 AA.
AC D5KB36;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=glutathione dehydrogenase (ascorbate) {ECO:0000256|ARBA:ARBA00012436};
DE EC=1.8.5.1 {ECO:0000256|ARBA:ARBA00012436};
DE Flags: Fragment;
GN Name=DHAR {ECO:0000313|EMBL:ADF42514.1};
OS Rosa roxburghii.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Rosoideae; Rosoideae incertae sedis;
OC Rosa.
OX NCBI_TaxID=74654 {ECO:0000313|EMBL:ADF42514.1};
RN [1] {ECO:0000313|EMBL:ADF42514.1}
RP NUCLEOTIDE SEQUENCE.
RA An H., Yu Y., Ming L.;
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 glutathione + L-dehydroascorbate = glutathione disulfide +
CC L-ascorbate; Xref=Rhea:RHEA:24424, ChEBI:CHEBI:38290,
CC ChEBI:CHEBI:57925, ChEBI:CHEBI:58297, ChEBI:CHEBI:58539; EC=1.8.5.1;
CC Evidence={ECO:0000256|ARBA:ARBA00000509};
CC -!- SIMILARITY: Belongs to the GST superfamily. DHAR family.
CC {ECO:0000256|ARBA:ARBA00024194}.
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DR EMBL; GU552460; ADF42514.1; -; mRNA.
DR AlphaFoldDB; D5KB36; -.
DR GO; GO:0045174; F:glutathione dehydrogenase (ascorbate) activity; IEA:UniProtKB-EC.
DR GO; GO:0004364; F:glutathione transferase activity; IEA:UniProtKB-EC.
DR GO; GO:0033355; P:ascorbate glutathione cycle; IEA:InterPro.
DR CDD; cd00570; GST_N_family; 1.
DR Gene3D; 1.20.1050.10; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR044627; DHAR1/2/3/4.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR004045; Glutathione_S-Trfase_N.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR44420; GLUTATHIONE S-TRANSFERASE DHAR2-RELATED; 1.
DR PANTHER; PTHR44420:SF6; REDUCTASE, PUTATIVE-RELATED; 1.
DR Pfam; PF13410; GST_C_2; 1.
DR Pfam; PF13409; GST_N_2; 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS50404; GST_NTER; 1.
PE 2: Evidence at transcript level;
KW Oxidoreductase {ECO:0000313|EMBL:ADF42514.1}.
FT DOMAIN 1..63
FT /note="GST N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50404"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADF42514.1"
FT NON_TER 136
FT /evidence="ECO:0000313|EMBL:ADF42514.1"
SQ SEQUENCE 136 AA; 15085 MW; 3417C503CD237FC4 CRC64;
VTLTLEEKKV PYKLHLINLA DKPQWFTEVN PEGKVPVVKF DDKWVSDSDV LAGILEEKYP
EPVLKTPPEF ASVGSKIFGS FVTFLKSKDP SDGSEQALLN ELKALDEHLK AHGPYIAGEK
VTAADLSLAP KLYHLK
//
