ID D5P8N0_9MYCO Unreviewed; 415 AA.
AC D5P8N0;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=HNH endonuclease domain protein {ECO:0000313|EMBL:EFG77572.1};
GN ORFNames=HMPREF0591_2524 {ECO:0000313|EMBL:EFG77572.1};
OS Mycobacterium parascrofulaceum ATCC BAA-614.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium simiae complex.
OX NCBI_TaxID=525368 {ECO:0000313|EMBL:EFG77572.1, ECO:0000313|Proteomes:UP000003653};
RN [1] {ECO:0000313|EMBL:EFG77572.1, ECO:0000313|Proteomes:UP000003653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-614 {ECO:0000313|EMBL:EFG77572.1,
RC ECO:0000313|Proteomes:UP000003653};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.
CC {ECO:0000256|ARBA:ARBA00023450}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFG77572.1}.
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DR EMBL; ADNV01000212; EFG77572.1; -; Genomic_DNA.
DR RefSeq; WP_007166557.1; NZ_GG770553.1.
DR AlphaFoldDB; D5P8N0; -.
DR eggNOG; COG1403; Bacteria.
DR HOGENOM; CLU_057500_1_0_11; -.
DR Proteomes; UP000003653; Unassembled WGS sequence.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00085; HNHc; 1.
DR Gene3D; 1.10.30.50; -; 1.
DR InterPro; IPR003870; DUF222.
DR InterPro; IPR002711; HNH.
DR InterPro; IPR003615; HNH_nuc.
DR Pfam; PF02720; DUF222; 1.
DR Pfam; PF01844; HNH; 1.
DR SMART; SM00507; HNHc; 1.
PE 3: Inferred from homology;
KW Endonuclease {ECO:0000313|EMBL:EFG77572.1};
KW Hydrolase {ECO:0000313|EMBL:EFG77572.1};
KW Nuclease {ECO:0000313|EMBL:EFG77572.1}.
FT DOMAIN 294..345
FT /note="HNH nuclease"
FT /evidence="ECO:0000259|SMART:SM00507"
FT REGION 136..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 367..415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 415 AA; 45294 MW; 805CC3885B667FD2 CRC64;
MSSIASPPAE LSPAERLDVL FEELAELAGQ RNAIDGRIVE IVAELDRDEL WGNTGARSVA
ALVVWKLGSS SANAHTIATV ARRFEEFPRC AQGMREGRLS LDQVGVIAAG GGEGSDEHYA
QLARVATVNQ LRTAIKLEPR PEPDSGPGPR PSITKNSDED FTCWRIKLPH LDAAKFDAAL
ASHRDALIAE WKRDHGDRDH GSEHGPPLPG TFEAFMRLVE AGWDAEAARR PHGQHTTVVV
HVDVERRAAA LHLGPLLTDA ERRYLGCDAT CEVWFERDGG VIGAGRATRT INRRLRRALE
HRQSTCAVPG CGATRGLHAH HIRHWEAGGP TELANLVLVC PYHHRLHHRG VITITGPAGA
LTVTDGRGRP LSAGSLARVP DRPPPRVPPC PGPTGERADW WWYDPFQPQP PPTHN
//
