ID D5Q5E2_CLODI Unreviewed; 94 AA.
AC D5Q5E2;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE RecName: Full=Cell division topological specificity factor {ECO:0000256|HAMAP-Rule:MF_00262};
GN Name=minE {ECO:0000256|HAMAP-Rule:MF_00262,
GN ECO:0000313|EMBL:EFH06813.1};
GN ORFNames=HMPREF0220_2124 {ECO:0000313|EMBL:EFH06813.1};
OS Clostridioides difficile NAP08.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC Clostridioides.
OX NCBI_TaxID=525259 {ECO:0000313|EMBL:EFH06813.1, ECO:0000313|Proteomes:UP000003227};
RN [1] {ECO:0000313|EMBL:EFH06813.1, ECO:0000313|Proteomes:UP000003227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NAP08 {ECO:0000313|EMBL:EFH06813.1,
RC ECO:0000313|Proteomes:UP000003227};
RA Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Prevents the cell division inhibition by proteins MinC and
CC MinD at internal division sites while permitting inhibition at polar
CC sites. This ensures cell division at the proper site by restricting the
CC formation of a division septum at the midpoint of the long axis of the
CC cell. {ECO:0000256|ARBA:ARBA00025265, ECO:0000256|HAMAP-Rule:MF_00262}.
CC -!- SIMILARITY: Belongs to the MinE family. {ECO:0000256|ARBA:ARBA00008168,
CC ECO:0000256|HAMAP-Rule:MF_00262}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFH06813.1}.
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DR EMBL; ADNX01000051; EFH06813.1; -; Genomic_DNA.
DR RefSeq; WP_003419058.1; NZ_GG770713.1.
DR AlphaFoldDB; D5Q5E2; -.
DR SMR; D5Q5E2; -.
DR GeneID; 66353561; -.
DR HOGENOM; CLU_137929_1_1_9; -.
DR Proteomes; UP000003227; Unassembled WGS sequence.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0032955; P:regulation of division septum assembly; IEA:InterPro.
DR Gene3D; 3.30.1070.10; Cell division topological specificity factor MinE; 1.
DR HAMAP; MF_00262; MinE; 1.
DR InterPro; IPR005527; MinE.
DR InterPro; IPR036707; MinE_sf.
DR NCBIfam; TIGR01215; minE; 1.
DR Pfam; PF03776; MinE; 1.
DR SUPFAM; SSF55229; Cell division protein MinE topological specificity domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|HAMAP-Rule:MF_00262};
KW Cell division {ECO:0000256|HAMAP-Rule:MF_00262,
KW ECO:0000313|EMBL:EFH06813.1}.
SQ SEQUENCE 94 AA; 10686 MW; 048E5D04DEAEDBB3 CRC64;
MLDLFRVFSN EAKTSKSVAK ERLKLVLVHD RVDCSPQLLE MIKTDILKVI ANYAEIEDDG
LEIKMSKCRG EHDDKPVSAL VANIPLKNIK DRCM
//