ID D5V2N3_ARCNC Unreviewed; 905 AA.
AC D5V2N3;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:ADG92465.1};
GN OrderedLocusNames=Arnit_0801 {ECO:0000313|EMBL:ADG92465.1};
OS Arcobacter nitrofigilis (strain ATCC 33309 / DSM 7299 / CCUG 15893 / LMG
OS 7604 / NCTC 12251 / CI) (Campylobacter nitrofigilis).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Arcobacteraceae; Arcobacter.
OX NCBI_TaxID=572480 {ECO:0000313|EMBL:ADG92465.1, ECO:0000313|Proteomes:UP000000939};
RN [1] {ECO:0000313|EMBL:ADG92465.1, ECO:0000313|Proteomes:UP000000939}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33309 / DSM 7299 / CCUG 15893 / LMG 7604 / NCTC 12251 / CI
RC {ECO:0000313|Proteomes:UP000000939};
RX PubMed=21304714; DOI=10.4056/sigs.912121;
RA Pati A., Gronow S., Lapidus A., Copeland A., Glavina Del Rio T., Nolan M.,
RA Lucas S., Tice H., Cheng J.F., Han C., Chertkov O., Bruce D., Tapia R.,
RA Goodwin L., Pitluck S., Liolios K., Ivanova N., Mavromatis K., Chen A.,
RA Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D., Detter J.C.,
RA Rohde M., Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of Arcobacter nitrofigilis type strain (CI).";
RL Stand. Genomic Sci. 2:300-308(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001999; ADG92465.1; -; Genomic_DNA.
DR RefSeq; WP_013134610.1; NC_014166.1.
DR AlphaFoldDB; D5V2N3; -.
DR STRING; 572480.Arnit_0801; -.
DR KEGG; ant:Arnit_0801; -.
DR eggNOG; COG2199; Bacteria.
DR eggNOG; COG2200; Bacteria.
DR eggNOG; COG4564; Bacteria.
DR HOGENOM; CLU_000445_70_46_7; -.
DR OrthoDB; 9790732at2; -.
DR Proteomes; UP000000939; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR004010; Double_Cache_2.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR033480; sCache_2.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF78; CYCLIC DI-GMP PHOSPHODIESTERASE PDEI-RELATED; 1.
DR Pfam; PF08269; dCache_2; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM01049; Cache_2; 2.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000939};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 398..449
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 450..504
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 528..660
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 664..905
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 905 AA; 106065 MW; D46BC5A05F33F6FB CRC64;
MKLTLSKINF INIFSIIVVF SIILGFFIYE FNQELYEKKV VSLEKSYFKK NKAIIKNEIE
RAIKRIEVIN NLIYEKNESI LKEKVSFVKN LFDSNKEKNF NIVLSKYKKE LNLFKWDNGT
GYFYIFDKNG KILYHGGNKK YVNTNVFESS KTNKELYDFL KETLILDENY GSYKWYKPNE
SPKEIFTKYV YIKKDEKYDV YIAAGVYKKE IDKKVQKLIF EEFKKDKFGD NKYGYFWILG
LDKVMKMHAL SPELEGKINN HVLSIKGKVL NDIAIKKALD GGGYINYKWI RPDTKKEDEK
FSYVKLIPKW NLLIGAGFYI TELQDILKEE KKSLRELSNE YLSKVFVVLI ILITISLFIA
RYLSVKIHNV ENEREEHMNM LKQYKLLLDR SSVVSKTDKD GIITYVNDSF EKTSGYNKNE
LIGISHKIIA HPDTPRSQSK KLWDTILKGK IWKGILKNKR KDGVSYYNSI TIIPIKDSQG
NIKEFISAGT IVTELIENRS KLKNLFKTDA LTGLGNRVSL IDHISKQQNG TLALINIDRF
KEINDSHSHV IGDKVITSLS DRLFRYFNDK GYDLYRLQSD IFALFTVNKD RRIDDINEFM
NTLGKEPYII GKETFILTYT CGIASNSENL LTYADIALTE AKNKKVKIKE YNNSMKNIEE
FKNNLLWVER LHLAIKENRI FPHYQPIYNY KTGKIDKYEA LMRLYLDGKI IYPNEYLDIA
KKTKLYPELT YKMVEEVISK FSTNNYEFSL NLCIEDLMNE ELMIYVFDYA EQKGVFKRMV
LEIVESEEID DSDYINKLLR RFKEEGVKIA IDDFGSGYSN YDYLIKLQAD YLKIDGSIIK
LIENDIRTQN VVKSIFEFAQ KSNIKVIAEF VSNENIDKIL REIGIDYAQG FYYGKPEAKL
IDEIN
//
