ID D5VSP4_METIM Unreviewed; 667 AA.
AC D5VSP4;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=acetate--CoA ligase (ADP-forming) {ECO:0000256|ARBA:ARBA00012957};
DE EC=6.2.1.13 {ECO:0000256|ARBA:ARBA00012957};
GN OrderedLocusNames=Metin_0939 {ECO:0000313|EMBL:ADG13597.1};
OS Methanocaldococcus infernus (strain DSM 11812 / JCM 15783 / ME).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanocaldococcaceae; Methanocaldococcus.
OX NCBI_TaxID=573063 {ECO:0000313|EMBL:ADG13597.1, ECO:0000313|Proteomes:UP000002061};
RN [1] {ECO:0000313|EMBL:ADG13597.1, ECO:0000313|Proteomes:UP000002061}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11812 / JCM 15783 / ME {ECO:0000313|Proteomes:UP000002061};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Munk A.C., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Woyke T.;
RT "Complete sequence of Methanocaldococcus infernus ME.";
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetate + ATP + CoA = acetyl-CoA + ADP + phosphate;
CC Xref=Rhea:RHEA:15081, ChEBI:CHEBI:30089, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288,
CC ChEBI:CHEBI:456216; EC=6.2.1.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001619};
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DR EMBL; CP002009; ADG13597.1; -; Genomic_DNA.
DR RefSeq; WP_013100343.1; NC_014122.1.
DR AlphaFoldDB; D5VSP4; -.
DR STRING; 573063.Metin_0939; -.
DR GeneID; 9131951; -.
DR KEGG; mif:Metin_0939; -.
DR eggNOG; arCOG01338; Archaea.
DR eggNOG; arCOG01340; Archaea.
DR HOGENOM; CLU_007415_3_1_2; -.
DR OrthoDB; 18103at2157; -.
DR Proteomes; UP000002061; Chromosome.
DR GO; GO:0043758; F:acetate-CoA ligase (ADP-forming) activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 2.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR003781; CoA-bd.
DR InterPro; IPR043938; Ligase_CoA_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032875; Succ_CoA_lig_flav_dom.
DR InterPro; IPR016102; Succinyl-CoA_synth-like.
DR PANTHER; PTHR43334; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR PANTHER; PTHR43334:SF1; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR Pfam; PF13549; ATP-grasp_5; 1.
DR Pfam; PF13380; CoA_binding_2; 1.
DR Pfam; PF19045; Ligase_CoA_2; 1.
DR Pfam; PF13607; Succ_CoA_lig; 1.
DR SMART; SM00881; CoA_binding; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 2.
DR PROSITE; PS50975; ATP_GRASP; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409}.
FT DOMAIN 476..553
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
FT COILED 423..469
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 667 AA; 74537 MW; 651187212CFC0F70 CRC64;
MFNPKAIAII GATPKEGKAG YSILKNLLKF KGKLYPINPK YSEIFGIKCY KSILDVDDKI
DLAIIVVPNV VVPQVLEECG KKGVKYVVII SAGFSEVGNV ELENKVRGIL KKYNIRAIGP
NCFGLINAHI NLNATFSKVF PEKGNISLIS QSGAVIDAIL DILPLLNIGV SKVVSLGNKI
DIQESDILEI LKDDEETRVI GIYLESLKDK NFLKVAKEVA KKKPIIVLKA GKSEAGKRAA
KSHTGALAGE NELYEAIFKQ CGFIITETFE EFVDALHVFS TQPEMRGNKV GIITNAGGFG
VLAADASESY NLELPEFSVK EELKEVLKNA NISNPLDIIG DATPERYEKV VKIVMKDKNM
DGYLIILTPQ EMTKPLEVAE KLVRVEKVKP LVTSFIGGVS VKGAKSFLRK HGIPSYITPE
NGVKALSNLY KFYKLKMREE NEEEIKEILE EFLNIKEENK EEIRELIKKG DEYSIKKLLS
LYNFPVPRGY IVESEEEAEE VAKKLGRVVL KALNVYHKTD VGAVIIDPED VREAYKNLAE
KFGNKILIEE YIDERGVELI FGGKRSLYPL FLVGLGGIFT EVLKDVSLAI PPVDRNYIRE
MLNELKGSKL LKGYRGIEVD LDYLIDLLFK LSIFFYIHDE IREIDLNPIL AYKDGAKILD
AKIVRGE
//
