ID   D5X782_THEPJ            Unreviewed;       288 AA.
AC   D5X782;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   SubName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000313|EMBL:ADG82452.1};
DE            EC=2.5.1.54 {ECO:0000313|EMBL:ADG82452.1};
GN   OrderedLocusNames=TherJR_1600 {ECO:0000313|EMBL:ADG82452.1};
OS   Thermincola potens (strain JR).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Thermincolaceae;
OC   Thermincola.
OX   NCBI_TaxID=635013 {ECO:0000313|EMBL:ADG82452.1, ECO:0000313|Proteomes:UP000002377};
RN   [1] {ECO:0000313|EMBL:ADG82452.1, ECO:0000313|Proteomes:UP000002377}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JR {ECO:0000313|EMBL:ADG82452.1,
RC   ECO:0000313|Proteomes:UP000002377};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA   Kyrpides N., Mikhailova N., Hazen T.C., Woyke T.;
RT   "Complete sequence of Thermincola sp. JR.";
RL   Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP002028; ADG82452.1; -; Genomic_DNA.
DR   AlphaFoldDB; D5X782; -.
DR   STRING; 635013.TherJR_1600; -.
DR   KEGG; tjr:TherJR_1600; -.
DR   eggNOG; COG2876; Bacteria.
DR   HOGENOM; CLU_062599_0_0_9; -.
DR   Proteomes; UP000002377; Chromosome.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016832; F:aldehyde-lyase activity; IEA:InterPro.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006268; DAHP_syn_2.
DR   NCBIfam; TIGR01361; DAHP_synth_Bsub; 1.
DR   PANTHER; PTHR43018; PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE; 1.
DR   PANTHER; PTHR43018:SF1; PROTEIN AROA(G); 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002377};
KW   Transferase {ECO:0000313|EMBL:ADG82452.1}.
FT   DOMAIN          17..262
FT                   /note="DAHP synthetase I/KDSA"
FT                   /evidence="ECO:0000259|Pfam:PF00793"
SQ   SEQUENCE   288 AA;  31524 MW;  EC284F4978DFA889 CRC64;
     MRHDALVSRE TKKDDTIVDI KGIKVGGNNI VMIAGPCAIE DKEQYLETAV ALKRLGAHML
     RGGAFKPRTS PYTFQGLAEE GLKIIAEAKE LTEMPVVTEV LDTRDVELIA RYCDVIQVGS
     RNMQNFVLLK EVGRSSLPVL LKRGLSATIE EWLLAAEYIM AEGNHNVILC ERGIRTFETY
     TRNTLDISAI PAVKHLSHLP VIVDPSHAAG RWGMVGPLSR SAVAAGADGL LIEVHPEPEL
     ALCDGGQSLT PENFAKLMKE VRAVAAAVDR TCDKEEKVSC QNKINMVR
//