ID D5X944_THEPJ Unreviewed; 1415 AA.
AC D5X944;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=CoA-substrate-specific enzyme activase {ECO:0000313|EMBL:ADG81044.1};
GN OrderedLocusNames=TherJR_0153 {ECO:0000313|EMBL:ADG81044.1};
OS Thermincola potens (strain JR).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Thermincolaceae;
OC Thermincola.
OX NCBI_TaxID=635013 {ECO:0000313|EMBL:ADG81044.1, ECO:0000313|Proteomes:UP000002377};
RN [1] {ECO:0000313|EMBL:ADG81044.1, ECO:0000313|Proteomes:UP000002377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JR {ECO:0000313|EMBL:ADG81044.1,
RC ECO:0000313|Proteomes:UP000002377};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Hazen T.C., Woyke T.;
RT "Complete sequence of Thermincola sp. JR.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CP002028; ADG81044.1; -; Genomic_DNA.
DR RefSeq; WP_013119072.1; NC_014152.1.
DR STRING; 635013.TherJR_0153; -.
DR KEGG; tjr:TherJR_0153; -.
DR eggNOG; COG1924; Bacteria.
DR eggNOG; COG3580; Bacteria.
DR eggNOG; COG3581; Bacteria.
DR HOGENOM; CLU_002393_1_0_9; -.
DR OrthoDB; 9802715at2; -.
DR Proteomes; UP000002377; Chromosome.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 2.
DR Gene3D; 3.30.420.40; -; 4.
DR InterPro; IPR002731; ATPase_BadF.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018709; CoA_activase_DUF2229.
DR InterPro; IPR008275; CoA_E_activase_dom.
DR NCBIfam; TIGR00241; CoA_E_activ; 1.
DR PANTHER; PTHR32329:SF4; ACTIVATOR OF 2-HYDROXYACYL-COA DEHYDRATASE-RELATED; 1.
DR PANTHER; PTHR32329; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR Pfam; PF01869; BcrAD_BadFG; 2.
DR Pfam; PF09989; DUF2229; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Iron {ECO:0000256|ARBA:ARBA00023014};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00023014};
KW Reference proteome {ECO:0000313|Proteomes:UP000002377}.
FT DOMAIN 7..255
FT /note="ATPase BadF/BadG/BcrA/BcrD type"
FT /evidence="ECO:0000259|Pfam:PF01869"
FT DOMAIN 322..576
FT /note="ATPase BadF/BadG/BcrA/BcrD type"
FT /evidence="ECO:0000259|Pfam:PF01869"
FT DOMAIN 672..890
FT /note="DUF2229"
FT /evidence="ECO:0000259|Pfam:PF09989"
FT COILED 816..843
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1415 AA; 158168 MW; F54C44489101F718 CRC64;
MNKVLHVGVD VGSTTVKMVI LDQDDNIVYK KYLRHLSDIK NTVFAMLEDA KKIMERNLLT
VMVTGSGGFS ISQRLEVPFI QEVIACVNAV RRKIPNTDVA IELGGEDAKI TYFGESIEQR
MNGTCAGGTG AFIDQMAALL QTDPMGLNEL AKKHKNIYPI ASRCGVFAKT DIQPLLNEGA
AKEDIAASVL QAVVNQTISG LAQGRPISGN VAFLGGPLHF MSELRKRFIE TLRLADESVI
FPDDSQFFVA LGAALSSREE TPMPFECFYE RAPRIYSLNN EDSENLEPLF ANEEEYREFS
ERHARHKVKR VELETYEGNA YLGIDAGSTT TKIALIDEAG NLLYSHYGSN MGSPLESTVE
ALKTLYSKMN SRTRIVNSAV TGYGEHLIKA ALKVDIGEIE TVAHYKAADF FLPGVDFVLD
IGGQDMKSLV IRDGVIDSIM LNEACSSGCG SFIETFAKSL NMDVKEFARL GLTAKKPVDL
GTRCTVFMNS KVKQAQKEGA DVGDISAGIS TSVIKNALFK VIRLRSADDL GEKIVVQGGT
FYNDAALRAM EKIIKRPVVR PDIAGLMGAF GAALIARERY VEGHTSSLLQ GEELDNFSTA
TSFKRCGLCG NNCLITVKTF SNGTEFVSGN RCERGAGKEK VANEVPNLYE YKYKRLFSYK
PLSKKEATRG VIGLPRVLNM YEDYPFWFTF FTELGYRVVI SGRSSKKIYE LGMETIPSES
TCYPAKLVHG HITDLINKGV KKIFYPCIPY NIKEDENADN KYNCPIVTSY PETINANMDI
LKQNNVIFYH PFLPLDMPKR MVKRLTEELA PEGIPKKEIA RALDKAYAEL ARYKEDVRRK
GEETIKYIEA NNIKGIVLVG RPYHIDPEIN HGIPEMVKSF GFAVLSEDSI RHLAEVERPL
RVVDQWVYHS RLYAAASFVA RQRNLELIQL NSFGCGLDAV TTDQVKEILE SYGKIYTVLK
IDEINNLGAA RIRVRSLIAA IKERDKRNFV PRKLYENPGK VIFTEEMKKT HTILAPQMSP
IHFQFLRTGF EKAGYKIVVL PSVDKTAIDE GLKYVHNDAC YPAIIVVGQL MKALNSGDYD
LKNTSVIITQ TGGGCRATNY IAFIRKALRD AGMGHVPVIS LNASGLEKQP GFKVTFSMFN
DLMMGLVYGD LLMRVLYRVR PYEKVPGSAN KLYEYWVDKC QEHLRKGGRK EFKENIYRIV
KDFDNLEIHE NMSKPRVGVV GEILVKFHPT ANNNIVELLE AEGAEAVVPD LTDFLMYSAF
DNKIKYEQLS GSFKKMISGS ISIKVMEAYR KHMRKALAAS KRFEPPKPIE EIARLAERHL
SLANQTGEGW FLTGEMVELI HSGVNNIVCL QPFACLPNHI TGKGMIRELR RAYPLANIAP
IDYDPGASEV NQLNRIKLML SVAMENLEKS NELKD
//
