ID D6AEF7_STRFL Unreviewed; 1289 AA.
AC D6AEF7;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=FtsK/SpoIIIE family protein {ECO:0000313|EMBL:EFE74683.2};
GN ORFNames=SSGG_02049 {ECO:0000313|EMBL:EFE74683.2};
OS Streptomyces filamentosus NRRL 15998.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=457431 {ECO:0000313|EMBL:EFE74683.2, ECO:0000313|Proteomes:UP000003986};
RN [1] {ECO:0000313|Proteomes:UP000003986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 15998 {ECO:0000313|Proteomes:UP000003986};
RA Molnar K.;
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000003986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 15998 {ECO:0000313|Proteomes:UP000003986};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Ward D., Young S., Kodira C.D., Zeng Q., Koehrsen M.,
RA Godfrey P., Alvarado L., Berlin A.M., Borenstein D., Chen Z., Engels R.,
RA Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.I.,
RA Hepburn T.A., Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D.,
RA Pearson M., Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C.,
RA Sykes S.N., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland B.L.C., Ilzarbe M.,
RA Galagan J., Nusbaum C., Birren B.;
RT "Annotation of Streptomyces roseosporus strain NRRL 15998.";
RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DS999644; EFE74683.2; -; Genomic_DNA.
DR Proteomes; UP000003986; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR023836; EccCa-like_Actinobacteria.
DR InterPro; IPR023837; EccCb-like_Actinobacteria.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR03924; T7SS_EccC_a; 1.
DR NCBIfam; TIGR03925; T7SS_EccC_b; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR PANTHER; PTHR22683:SF1; TYPE VII SECRETION SYSTEM PROTEIN ESSC; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 2.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR PROSITE; PS50901; FTSK; 3.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 425..626
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT DOMAIN 785..976
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT DOMAIN 1071..1256
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 692..711
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 448..455
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT BINDING 803..810
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT BINDING 1089..1096
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 1289 AA; 139218 MW; 6AC5C85EA87305FD CRC64;
MLPVAGVMSS VVMMTVVRNS QFAALGAIIL VVTVIGSVAL LFSQRGKAQR TRRTQREAYL
AYVEDLREEL SGEERERRER ADVLNPPPYA LYDIVRDPAR LWERRRVDDD FLRVRVGTGE
MPVRNLQIAE PGSTVLTPPD LFMLNEASAL VNRFRNGTEL PLTVPLDRIG NVSVIGPRED
CLRVARALLV QTAALHAPDD VAIALAAPGD RMADWEWAKW LPHLLDTEQF DGPVAARRIA
PSAPQLARQI GAELRRRASY AAEVRRGLAG RDALSMNSRL LVVTDGHGED AVDLPRPDDA
VGLREMGVTV LHLLEQRVQE PGHVSVRITV DGADVTIEDL RTPEPVEAHG TVDEAGIPFA
EGLARMLAPL RLSAESLGDA PLSGPVEFAA MLGINDVARL DLDRLWAPRG ERAFLRVPIG
ISDSHEPVLL DLKESSELGM GPHGLCVGAT GSGKSELLRT LVLALVATHP PEDLALVLVD
YKGGATFAPF AELPHVAGVI TNLENQAGLV ERVHSSLAGE VKRRQQALKD AGNVADIGDY
AALRAGKRPD LDPLPHLFVV IDEFGELLTA KPDFIDLFLS IGRIGRSIGV HLLLSSQRIE
GGKLKGLDTY LSYRLGLRTF SADESRTVLE TTDAFHLPPL PGFGYLKVDT SHYARFKAGY
VSGGYRGPAR RHDEEETGPL ALPYEAFNTL AGPDEARQSP EPASRRRETG PTELGIMVDQ
LTGAAAAVRS IWLPPLPTAT ALDTVAGPLD IGPNGMRLTG AVAEGRRTPL RVPVGLLDDP
ARQWQGQWFL DLTVAGGHAA VIGGPQSGKT TLLRTLVLSL ALTHTPREIG VYGLDLVGGG
LQALSGLPHV GGIAGRADRE RAARTVEEVR TMLALREDLF REHGIDSVDQ LRTLHAAGRL
PELASAEILL VIDGFGALRD DFDELDDAIA DILKRGGGYG IHVVAGMLRW NDVRIAIQSN
FGTRVELRLN DPGESGIDRK LAETLSPDEP GRVLTDGKLF AQVALPRTDG VDDTTGLGAV
LERTARTVRA TWNGEVAQPV RVLPQVLEPH SLPGPAAEPT RVPIGLDQSA LAPVLLDLFS
HDQHLLVLGD SECGKTNLLR TVAHGLVDRY GEDDLVFAVM DPRRSLRGVV PEEFNGGYAY
NSKLCAGLSA AITTELEKRL PDENARLEDL EPGNWGKGPR IVVLVDDYDV LTTAGQSPLS
PFLPYIPSAV DIGLHFVLTR RVAGASRGMY EPLVQGLRES GASALLMAGD RSEGQLFPGV
YASQQAPGRG VFIRRGQPNR LIQTVYAPM
//
