ID   D6APY3_STRFL            Unreviewed;       730 AA.
AC   D6APY3;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=Phosphodiesterase {ECO:0000313|EMBL:EFE77795.2};
DE   Flags: Fragment;
GN   ORFNames=SSGG_05162 {ECO:0000313|EMBL:EFE77795.2};
OS   Streptomyces filamentosus NRRL 15998.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=457431 {ECO:0000313|EMBL:EFE77795.2, ECO:0000313|Proteomes:UP000003986};
RN   [1] {ECO:0000313|Proteomes:UP000003986}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 15998 {ECO:0000313|Proteomes:UP000003986};
RA   Molnar K.;
RL   Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000003986}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 15998 {ECO:0000313|Proteomes:UP000003986};
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Microbial Sequencing Center;
RA   Fischbach M., Ward D., Young S., Kodira C.D., Zeng Q., Koehrsen M.,
RA   Godfrey P., Alvarado L., Berlin A.M., Borenstein D., Chen Z., Engels R.,
RA   Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.I.,
RA   Hepburn T.A., Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D.,
RA   Pearson M., Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C.,
RA   Sykes S.N., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA   Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland B.L.C., Ilzarbe M.,
RA   Galagan J., Nusbaum C., Birren B.;
RT   "Annotation of Streptomyces roseosporus strain NRRL 15998.";
RL   Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS999644; EFE77795.2; -; Genomic_DNA.
DR   AlphaFoldDB; D6APY3; -.
DR   Proteomes; UP000003986; Unassembled WGS sequence.
DR   CDD; cd01948; EAL; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   Pfam; PF00563; EAL; 1.
DR   SMART; SM00052; EAL; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   PROSITE; PS50883; EAL; 1.
PE   4: Predicted;
FT   DOMAIN          428..680
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
FT   REGION          1..409
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          701..730
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        81..96
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        130..160
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        193..231
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        242..258
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        330..395
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EFE77795.2"
SQ   SEQUENCE   730 AA;  79007 MW;  28C5565EA40AAD0C CRC64;
     EGRNETDRER RPGVAAARFR RPHAPGGRRR RGDRRVTAGG RVLPDRPAGP GALPERGGRL
     VLRRAHRDHR RPSGGPRPRP LVGRHRLRRR PHPRRAPAVR LAAGRPGQPR RRGARRDRPP
     APLVAGAAAR RGRHARHRRG GARAGRVRRG PHRRGALAAT RLGHRGRPGT APDRVDVSAR
     HPGPAVVRPG PAQRRAADHR PDRDAAPGAR RRRAPRARPA DLRRRDVHAH PAAALRGAAD
     RPGLHALDRP RPRRGAVARP ADRAAQPPVA AGADLVGAGG RRIHRHPLRA GPHRPGPLPR
     GQRHPRPSGR GPAAAPDSGA PAARPAARRG GGPPRRRRVR RPPPAHRLHH QRPAGRPASR
     RRAVLAARPR RAHPRPGGQR RGRRLPRPRP GRRRAAAPGG RRDVPGQAGT ARAWEVYESK
     RDSNTPDRLG LLGDLRRALD AGEVELHYQP KVRFDGQVAG LEALVRWVHP ERGRVPPDEF
     IAIAESSGLM PHLTEYVLET ALAQVARWRA QGLFVPVAVN VSPRDVHTPG FAGGVAARLA
     RHGVPAGALQ LEITEHVLLE DPQRAADTLA GLTAHGVKMS LDDFGTGYSS LVHLRRLPVS
     ELKIDRSFVA RLAVDHEDAE IVRCTIDLAH SLGLVVVAEG VEDDTTWERL RDLRCDAVQG
     WLVAAAMPPQ ETTAWLRARG EHGWRRPAEL KAQAAAAAGS ATASATGSMN GSLNGAVNGA
     VNSAAETDTP
//