ID D6BD08_9FUSO Unreviewed; 395 AA.
AC D6BD08;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Methyltransferase {ECO:0000256|RuleBase:RU362026};
DE EC=2.1.1.- {ECO:0000256|RuleBase:RU362026};
GN ORFNames=PSAG_00090 {ECO:0000313|EMBL:EFD80055.1};
OS Fusobacterium animalis D11.
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae;
OC Fusobacterium.
OX NCBI_TaxID=556264 {ECO:0000313|EMBL:EFD80055.1, ECO:0000313|Proteomes:UP000004650};
RN [1] {ECO:0000313|Proteomes:UP000004650}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D11 {ECO:0000313|Proteomes:UP000004650};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L.,
RA Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T.,
RA White J., Yandava C., Allen-Vercoe E., Strauss J., Sibley C., White A.,
RA Ambrose C., Lander E., Nusbaum C., Galagan J., Birren B.;
RT "The Genome Sequence of Shigella sp. D9.";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EFD80055.1, ECO:0000313|Proteomes:UP000004650}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D11 {ECO:0000313|EMBL:EFD80055.1,
RC ECO:0000313|Proteomes:UP000004650};
RG The Broad Institute Genomics Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Kostic A., Garrett W.,
RA Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J., Gnerre S.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusobacterium nucleatum subsp. animalis D11.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594, ECO:0000256|RuleBase:RU362026}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFD80055.1}.
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DR EMBL; ACDS02000077; EFD80055.1; -; Genomic_DNA.
DR AlphaFoldDB; D6BD08; -.
DR HOGENOM; CLU_029607_2_0_0; -.
DR Proteomes; UP000004650; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002941; DNA_methylase_N4/N6.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR001091; RM_Methyltransferase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR13370:SF32; DNA ADENINE METHYLTRANSFERASE YHDJ; 1.
DR PANTHER; PTHR13370; RNA METHYLASE-RELATED; 1.
DR Pfam; PF01555; N6_N4_Mtase; 1.
DR PRINTS; PR00508; S21N4MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:EFD80055.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 8..264
FT /note="DNA methylase N-4/N-6"
FT /evidence="ECO:0000259|Pfam:PF01555"
FT COILED 300..353
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 395 AA; 46418 MW; A1CDC179FC36327D CRC64;
MKNWGGGVKC IYIDPPYNTG SDSFNYNDNF NHSTWLTFMK NRLELAKKLL TDDGSIFINL
DYNEVHYCKV LMDDIFGREN FQREIIWRIG WVSGYKTSVN NYIRNHDTIL FYSKNKEFYF
NKQYILNSEF KNLVKKDKVK SEFEKLNIDD DLQDKLLNII NYKTRPERYP LEDVWNANEY
DDLNSIAIVS YSGESVSKML KIENDIKGQK SEKLIERIIK NSTMEGDTIL DFHLGSGTTA
AVAHKMGRRY IGIEQMDYIE DIVVERLKKV INGEQGGISK AVNWQGGGSF VYCELKENSY
ILLNKIKEAT EENIKKVKDE IYKDERIIPY ITREELEKAN KDFENLKLED KKKILIDLVD
KNKLYVNYSD MEDEEYSISE NEKIFTNSFY KGDIK
//
