ID   D6EKN6_STRLI            Unreviewed;       485 AA.
AC   D6EKN6;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=Permease {ECO:0000313|EMBL:EFD65816.2};
GN   ORFNames=SSPG_01456 {ECO:0000313|EMBL:EFD65816.2};
OS   Streptomyces lividans TK24.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=457428 {ECO:0000313|EMBL:EFD65816.2};
RN   [1] {ECO:0000313|EMBL:EFD65816.2}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TK24 {ECO:0000313|EMBL:EFD65816.2};
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Microbial Sequencing Center;
RA   Fischbach M., Godfrey P., Ward D., Young S., Kodira C.D., Zeng Q.,
RA   Koehrsen M., Alvarado L., Berlin A.M., Borenstein D., Chen Z., Engels R.,
RA   Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.I.,
RA   Hepburn T.A., Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D.,
RA   Pearson M., Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C.,
RA   Sykes S.N., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA   Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA   Galagan J., Nusbaum C., Birren B.;
RT   "The genome sequence of Streptomyces lividans strain TK24.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
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DR   EMBL; GG657756; EFD65816.2; -; Genomic_DNA.
DR   RefSeq; WP_003972750.1; NZ_GG657756.1.
DR   AlphaFoldDB; D6EKN6; -.
DR   HOGENOM; CLU_024508_0_0_11; -.
DR   Proteomes; UP000002769; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR   InterPro; IPR045018; Azg-like.
DR   InterPro; IPR006043; NCS2.
DR   PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR   PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
SQ   SEQUENCE   485 AA;  49975 MW;  E2D3EC1F28E7F6E1 CRC64;
     MTQQSVEPEI TAEDAGAGSR VPGGRSWLDR YFHISHRGST VAREVRGGIT TFMAMAYIVL
     LNPVILSGKD AAGDTLGQKA LITATAFAAA LTTLLMGFVG KVPLALAAGL SVSGVIAGQV
     VPQMTWPQAM GMCVMYGVVI MLLVVTGLRE MIMNAIPLAL KHGITMGIGL FIAIIGLVKG
     GFVHAGEATP LTLGPAGELA GWPVLLFAGT LLLIFMLQAR NMPGAILIGI VTGTIVAAVL
     NATGVIDPEQ WANGAPELHG SAVSMPDFSL FGDLEFGGWG EVGAMTVGMI VFTLVLAGFF
     DAMATIIGVG TEAKLADDKG RMPGLSKALF IDGAGGAIGG VAGGSGQTVF VESATGVGEG
     ARTGLASVVT GLFFAACLFF TPITAIVPQE VASAALVVIG AMMMMNARHV DWADRATAIP
     VFLTVVLMPF TYSITAGVAA GVISYVAIKV AQGRAREIGA FMWALTVIFV VYFALNPIES
     WLGVH
//