ID   D6ETZ4_STRLI            Unreviewed;       693 AA.
AC   D6ETZ4;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   SubName: Full=Hydrolase {ECO:0000313|EMBL:EFD70863.2};
GN   ORFNames=SSPG_06503 {ECO:0000313|EMBL:EFD70863.2};
OS   Streptomyces lividans TK24.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=457428 {ECO:0000313|EMBL:EFD70863.2};
RN   [1] {ECO:0000313|EMBL:EFD70863.2}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TK24 {ECO:0000313|EMBL:EFD70863.2};
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Microbial Sequencing Center;
RA   Fischbach M., Godfrey P., Ward D., Young S., Kodira C.D., Zeng Q.,
RA   Koehrsen M., Alvarado L., Berlin A.M., Borenstein D., Chen Z., Engels R.,
RA   Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.I.,
RA   Hepburn T.A., Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D.,
RA   Pearson M., Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C.,
RA   Sykes S.N., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA   Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA   Galagan J., Nusbaum C., Birren B.;
RT   "The genome sequence of Streptomyces lividans strain TK24.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC       {ECO:0000256|ARBA:ARBA00007401}.
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DR   EMBL; GG657756; EFD70863.2; -; Genomic_DNA.
DR   RefSeq; WP_003977768.1; NZ_GG657756.1.
DR   AlphaFoldDB; D6ETZ4; -.
DR   HOGENOM; CLU_009935_2_1_11; -.
DR   Proteomes; UP000002769; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR006103; Glyco_hydro_2_cat.
DR   InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR   InterPro; IPR006104; Glyco_hydro_2_N.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR   PANTHER; PTHR42732:SF3; BETA-MANNOSIDASE; 1.
DR   Pfam; PF00703; Glyco_hydro_2; 1.
DR   Pfam; PF02836; Glyco_hydro_2_C; 1.
DR   Pfam; PF02837; Glyco_hydro_2_N; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EFD70863.2}.
FT   DOMAIN          22..178
FT                   /note="Glycosyl hydrolases family 2 sugar binding"
FT                   /evidence="ECO:0000259|Pfam:PF02837"
FT   DOMAIN          181..275
FT                   /note="Glycoside hydrolase family 2 immunoglobulin-like
FT                   beta-sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF00703"
FT   DOMAIN          277..436
FT                   /note="Glycoside hydrolase family 2 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF02836"
SQ   SEQUENCE   693 AA;  75868 MW;  4ED9C7022A14CFE9 CRC64;
     MTTPRPEYPR PHFDRSHSWL TLNGTWDFRA DPAEAYSADA SDGYDRAITV PFAWETPASG
     IAEHWLRTAW YRRTFTVPAD WAGQRVVLHF GAVHHAATVW VNGTEVAHHE GGYTPFAADV
     TDALGDGEHQ LTVRVHAPAD KRDIAHGKQR SMPRDDYDGV CFTPSSGIWQ SVWLEARPAT
     HLAALRLRPN DDLTGITVEA VVHGPAADRA ELRLRVRDED TAVTATLGPD GRLATELPLS
     APRLWSPEDP HLYHVDAELT SADGTDRVAT YTGLRTVTVD GESLYLNGRR LFVRGVLDQG
     YWPETGITAP DDAALRRDIE LAAEAGYNLV RKHLKLEDPR FAHHADTLGM LLWAEPASPG
     RFSPASTAAF AEQIEPMVER DGNSPAIVIW GLYNEEWGLD WDIPGDPAKQ RATADAYDRL
     KALDATRPVV DNSGWTHVKT DLLDWHYYDE SAASWATTVA DLLSGERDDF PVKLGPDFVV
     HKKLAVPGQP LRGLPNLNSE YGGGFTGLDR AWHLRWQTQE LRRHDRLAGY VYTELYDIEH
     ESAGLLDFGR GAKDLAGVDP AHANAPTTLV LDVTPVAPGR DLLTTGPDFT VDVHVSHHGD
     DPVAGTVHTT WTPVYARTPD APGDAVPGCR AEAKPYVLGA AVTVPAALPD GWTSGRLHLA
     LVVDGTVAAR TALDVDTRTD PYIGDDPQAR PTA
//