ID D6K8D7_9ACTN Unreviewed; 457 AA.
AC D6K8D7;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Monooxygenase {ECO:0000313|EMBL:EFF94177.2};
GN ORFNames=SSTG_04497 {ECO:0000313|EMBL:EFF94177.2};
OS Streptomyces sp. e14.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=645465 {ECO:0000313|EMBL:EFF94177.2, ECO:0000313|Proteomes:UP000004704};
RN [1] {ECO:0000313|EMBL:EFF94177.2, ECO:0000313|Proteomes:UP000004704}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=e14 {ECO:0000313|Proteomes:UP000004704};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Streptomyces sp. strain e14.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NtaA/SnaA/DszA monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00033748}.
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DR EMBL; GG753626; EFF94177.2; -; Genomic_DNA.
DR RefSeq; WP_009191717.1; NZ_GG753626.1.
DR AlphaFoldDB; D6K8D7; -.
DR STRING; 645465.SSTG_04497; -.
DR eggNOG; COG2141; Bacteria.
DR OrthoDB; 3265338at2; -.
DR Proteomes; UP000004704; Unassembled WGS sequence.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd01095; Nitrilotriacetate_monoxgenase; 1.
DR Gene3D; 3.20.20.30; Luciferase-like domain; 1.
DR InterPro; IPR011251; Luciferase-like_dom.
DR InterPro; IPR036661; Luciferase-like_sf.
DR InterPro; IPR016215; NTA_MOA.
DR NCBIfam; TIGR03860; FMN_nitrolo; 1.
DR PANTHER; PTHR30011; ALKANESULFONATE MONOOXYGENASE-RELATED; 1.
DR PANTHER; PTHR30011:SF16; C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED; 1.
DR Pfam; PF00296; Bac_luciferase; 1.
DR PIRSF; PIRSF000337; NTA_MOA; 1.
DR SUPFAM; SSF51679; Bacterial luciferase-like; 1.
PE 3: Inferred from homology;
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR000337-1};
KW FMN {ECO:0000256|PIRSR:PIRSR000337-1};
KW Monooxygenase {ECO:0000313|EMBL:EFF94177.2};
KW Oxidoreductase {ECO:0000313|EMBL:EFF94177.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000004704}.
FT DOMAIN 27..395
FT /note="Luciferase-like"
FT /evidence="ECO:0000259|Pfam:PF00296"
FT BINDING 97
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
FT BINDING 151
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
FT BINDING 222
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
SQ SEQUENCE 457 AA; 50640 MW; BF181C0F638A89E4 CRC64;
MSKPLKQIHL AAHFPGVNNT TVWSDPAAGS HIEFSSFAHF ARTAERAKFD FLFLAEGLRL
REQGGEIYDL DVVGRPDTFT VLAALAAVTD RLGLTGTINS TFNEPYEVAR QFASLDHLSG
GRSAWNVVTS WDAFTGENFR RGGFLPKEER YARAKEFLAT AGELFDSWHG DEIVADQATG
VFLRDAKAGA FVHQGPQFDI HGQFDVPRSP QGRPVIFQAG DSEEGREFAA SGADAIFSRY
ASWDDGRAFY RDVKSRLAKY GRRDDQLLIL PAATFVLGDT DAEAEELAHE VRRQQVSGAT
AIKHLEFVWN RDLSSYDPEG PLPDIDPDTG EDHIARGRAQ VRMYRDPLAT AREWRELAAA
NNWSIRDLVI HTGNRQTFVG SPATVAKTIN EFVQGDVSDG FILVPHITPG GLDPFADKVV
PLLQEQGVFR ADYEGTTLRD HLGLDHPDEA RERRVAS
//
