ID D6K9D1_9ACTN Unreviewed; 518 AA.
AC D6K9D1;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Monooxygenase, FAD-binding {ECO:0000313|EMBL:EFF94264.2};
GN ORFNames=SSTG_04584 {ECO:0000313|EMBL:EFF94264.2};
OS Streptomyces sp. e14.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=645465 {ECO:0000313|EMBL:EFF94264.2, ECO:0000313|Proteomes:UP000004704};
RN [1] {ECO:0000313|EMBL:EFF94264.2, ECO:0000313|Proteomes:UP000004704}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=e14 {ECO:0000313|Proteomes:UP000004704};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Streptomyces sp. strain e14.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; GG753626; EFF94264.2; -; Genomic_DNA.
DR RefSeq; WP_009191804.1; NZ_GG753626.1.
DR AlphaFoldDB; D6K9D1; -.
DR STRING; 645465.SSTG_04584; -.
DR eggNOG; COG0654; Bacteria.
DR OrthoDB; 8670884at2; -.
DR Proteomes; UP000004704; Unassembled WGS sequence.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.2450; -; 1.
DR Gene3D; 3.40.30.120; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR43004:SF6; FAD_NAD(P)-BINDING OXIDOREDUCTASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR43004; TRK SYSTEM POTASSIUM UPTAKE PROTEIN; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR Pfam; PF21274; Rng_hyd_C; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Monooxygenase {ECO:0000313|EMBL:EFF94264.2};
KW Oxidoreductase {ECO:0000313|EMBL:EFF94264.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000004704}.
FT DOMAIN 8..342
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
FT REGION 494..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 501..518
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 518 AA; 56960 MW; D5791D43F17BB543 CRC64;
MSADPAAATV AVIGAGPTGL ALACELAAAG VHCRVLEKRP RRVAWSRAMG LEPRTLEMFD
MRGMAEAFVD RGRPWRLQPL GDRAHHLDYA LLDTSFPYVL ILSQHHTEEL LEKRAVELGA
EIVRDAELTG LTQDDTGVTL EVRGPDRRRT ERAAYVVGCD GVRSRVRELS GIGFTGRSYR
ESLVVADVRL TAPPAALVDA RIAPRGLVAV FPLDDGVFRL VVLDRDRMRL PVEQPVKPEE
LTDSVLAVFG EDLGVGEVVW ASRFRSDQRL ADRYREGRVL LAGDAAHTHL PSGGQGLQMG
IQDAFNLGWK LAAEVQGRAP AALLDSYEAE RAPVARRVLR QTDRAFRFET SRSALANAAR
WAGMRLMRVR PLQRPLIDDL AGLTLRYRPA SGATTGRMTG RRLPDTPLYG AGPSVTRLYE
QLRDQRFLLV DQSPDGRAAA VAGHWAGPVR TVRAVAGGRR RWPTALLLRP DGHVAWSGDG
ARPEGLRDAL HTWLGEAPQR PEPRLPERTM DDAMEETA
//
