ID   D6QYN6_9MUSC            Unreviewed;       126 AA.
AC   D6QYN6;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Transmembrane protein 188 {ECO:0000256|ARBA:ARBA00030458};
OS   Drosophila pseudoobscura.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7237 {ECO:0000313|EMBL:ADG65056.1};
RN   [1] {ECO:0000313|EMBL:ADG65056.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=KB10 1105 {ECO:0000313|EMBL:ADG65056.1}, and MV2 1109
RC   {ECO:0000313|EMBL:ADG65058.1};
RX   PubMed=20351054; DOI=10.1093/molbev/msq085;
RA   Meisel R.P., Hilldorfer B.B., Koch J.L., Lockton S., Schaeffer S.W.;
RT   "Adaptive evolution of genes duplicated from the Drosophila pseudoobscura
RT   neo-X chromosome.";
RL   Mol. Biol. Evol. 0:0-0(2010).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CNEP1R1 family.
CC       {ECO:0000256|ARBA:ARBA00010998}.
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DR   EMBL; HM017705; ADG65056.1; -; Genomic_DNA.
DR   EMBL; HM017707; ADG65058.1; -; Genomic_DNA.
DR   AlphaFoldDB; D6QYN6; -.
DR   ExpressionAtlas; D6QYN6; baseline.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0071595; C:Nem1-Spo7 phosphatase complex; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0035307; P:positive regulation of protein dephosphorylation; IEA:InterPro.
DR   InterPro; IPR019168; NEP1-R1.
DR   PANTHER; PTHR20996:SF1; NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1; 1.
DR   PANTHER; PTHR20996; UNCHARACTERIZED; 1.
DR   Pfam; PF09771; Tmemb_18A; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        31..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   126 AA;  14247 MW;  9DA290718D74E5F6 CRC64;
     MEPSDDEDLK AFELRLTEVV LSHRPTFRWR ILLSAMSICT AIGAWYWLRD PHTTVVPLTE
     SLWIHPIFAA ATVTLIVLFI IGIQKLVIVP KVITTRARCV LGDFNMSCDD TGKLILKSRQ
     SYDGST
//