ID D6RE75_HUMAN Unreviewed; 142 AA.
AC D6RE75;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=WD repeat domain 19 {ECO:0000313|Ensembl:ENSP00000426918.1};
DE Flags: Fragment;
GN Name=WDR19 {ECO:0000313|Ensembl:ENSP00000426918.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000426918.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000426918.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15815621; DOI=10.1038/nature03466;
RA Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA Wilson R.K.;
RT "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT 4.";
RL Nature 434:724-731(2005).
RN [2] {ECO:0000313|Ensembl:ENSP00000426918.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC093855; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; D6RE75; -.
DR SMR; D6RE75; -.
DR MassIVE; D6RE75; -.
DR MaxQB; D6RE75; -.
DR PeptideAtlas; D6RE75; -.
DR ProteomicsDB; 14245; -.
DR Antibodypedia; 23402; 135 antibodies from 20 providers.
DR Ensembl; ENST00000509560.5; ENSP00000426918.1; ENSG00000157796.18.
DR UCSC; uc062vzh.1; human.
DR HGNC; HGNC:18340; WDR19.
DR VEuPathDB; HostDB:ENSG00000157796; -.
DR GeneTree; ENSGT00590000083165; -.
DR HOGENOM; CLU_1820205_0_0_1; -.
DR OMA; CTGFGWD; -.
DR ChiTaRS; WDR19; human.
DR Proteomes; UP000005640; Chromosome 4.
DR Bgee; ENSG00000157796; Expressed in right uterine tube and 179 other cell types or tissues.
DR ExpressionAtlas; D6RE75; baseline and differential.
DR GO; GO:0005929; C:cilium; IEA:GOC.
DR GO; GO:0035721; P:intraciliary retrograde transport; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR040379; WDR19/dyf-2.
DR PANTHER; PTHR14920; OSMOTIC AVOIDANCE ABNORMAL PROTEIN 1/WD REPEAT MEMBRANE PROTEIN; 1.
DR PANTHER; PTHR14920:SF2; WD REPEAT-CONTAINING PROTEIN 19; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR SMART; SM00320; WD40; 2.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:D6RE75,
KW ECO:0007829|MaxQB:D6RE75};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 1..89
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT NON_TER 142
FT /evidence="ECO:0000313|Ensembl:ENSP00000426918.1"
SQ SEQUENCE 142 AA; 15940 MW; B0026196BC4EC06C CRC64;
MDWDKDGDVL AVIAEKSSCI YLWDANTNKT SQLDNGMRDQ MSFLLWSKVG SFLAVGTVKG
NLLIYNHQTS RKIPVLGKHT KRITCGCWNA ENLLALGGED KMITVSNQEG DTIRQTQVRS
EPSNMQFFLM KMDDRTSAAE SM
//
