ID D6Y2R7_THEBD Unreviewed; 1461 AA.
AC D6Y2R7;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=ATPase, P-type (Transporting), HAD superfamily, subfamily IC {ECO:0000313|EMBL:ADG86878.1};
DE EC=3.6.3.8 {ECO:0000313|EMBL:ADG86878.1};
GN OrderedLocusNames=Tbis_0146 {ECO:0000313|EMBL:ADG86878.1};
OS Thermobispora bispora (strain ATCC 19993 / DSM 43833 / CBS 139.67 / JCM
OS 10125 / KCTC 9307 / NBRC 14880 / R51).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Thermobispora.
OX NCBI_TaxID=469371 {ECO:0000313|EMBL:ADG86878.1, ECO:0000313|Proteomes:UP000006640};
RN [1] {ECO:0000313|EMBL:ADG86878.1, ECO:0000313|Proteomes:UP000006640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19993 / DSM 43833 / CBS 139.67 / JCM 10125 / KCTC 9307 /
RC NBRC 14880 / R51 {ECO:0000313|Proteomes:UP000006640};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Mikhailova N., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F.,
RA Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T.,
RA Wu D., Jando M., Schneider S., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Thermobispora bispora DSM 43833.";
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00001836};
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP001874; ADG86878.1; -; Genomic_DNA.
DR RefSeq; WP_013130411.1; NC_014165.1.
DR STRING; 469371.Tbis_0146; -.
DR KEGG; tbi:Tbis_0146; -.
DR eggNOG; COG0474; Bacteria.
DR eggNOG; COG2217; Bacteria.
DR HOGENOM; CLU_002360_0_1_11; -.
DR OrthoDB; 9814270at2; -.
DR Proteomes; UP000006640; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 2.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 2.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR42861; CALCIUM-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR42861:SF29; SECRETORY PATHWAY CALCIUM ATPASE, ISOFORM G; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00690; Cation_ATPase_N; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00120; HATPASE.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SMART; SM00831; Cation_ATPase_N; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000313|EMBL:ADG86878.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006640};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1333..1351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1386..1406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1418..1437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 601..672
FT /note="Cation-transporting P-type ATPase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00831"
SQ SEQUENCE 1461 AA; 154609 MW; 379D2550266DEF30 CRC64;
MFLTQLFASY APVLRDVLPE PLRGLVVTPR RVIACPGGLR IDLRGIGGPG TERSAALLEE
RLSALPGVER AEVNGRLGCV FVGCDPEAVD REELLEIARE LDEQERHAHE TPVRVVEEHI
RSIIRLATGV AGVGTIFTGI ALRAPRLSPA VPALVNLLNA TPVLREELDK RIGRGPANAL
FHTANLVTQT LTLRPLGLVA HSMAALSRYV ETRAAQRSWV ALERRLAEVP GSYRHVRARF
RRRPTHLPHG PIERYADLAS TAAALTYGFM RFAARQDERA LAVLTAITPK IAEYTREAFA
GAVRRALGER DTVVFDAEAL RRMDRVDTVV LDSDALTTGS WAIDRVEPLV DELDLNELYA
RLYRLLDFTD PGATRIDEEW SAAPLTDPAR FPGTHATEWR GRGMRLVEVR RADTPVALVG
LSREIDPLAV PIVAAAKAAG TVLLAGDEDG TAHRLAIDQV LPGGADLAHR VFEMQAEGHC
VLVVSRRARE ALAQADIGFG VMDPGTATVP WDADVAGGLP GLHLLLIGLR RAETASRDGV
RIGVAGGLIG ALFSFAGPAS GAVGRAQLVS SLGALVAVAW GELAGRALAR TPVPLRADPT
PWHAMSVPEV LARLGSSPRG ISEEEAERRR AAARPVEIAA PRSLARTVLG ELANPLTPAL
ASGAAIAALI GSAVDSVMIS GVMVINAFIG GVQQSQADRE LTRLTETTSV RVRVRRPEGT
VEIRKEDLVP GDVVELRAGD AIPADGRVIK SVGLEVDEST LTGESQLIAK RTEPTIAAAI
ADRASMVYEG TTVAAGTGLA VVVATGEMTE ARRAAQLGTA PPRVSGVELR MRELSRRVLP
LSVGSGLFLL VTELLRGRSL AAALVPAVSL TVAAVPEGLP FVATAAELAA ARRLSRRAAL
VRNPKTIEAL GRVNVLCFDK TGTLTEGRIS LQYVSDGRAG RPVEELTHHL RRVIAAAVRA
SPKTGGGRVL AHPTDRAIHE AAERLSITPR EGLQVWERVD EMPFEPGRGY HAVLGRTEHG
HLLSVKGAPE IVIDHCTTAL RGTEVVPCDD AVRHELTREV ARLARQGYRV LAVAQRPASD
RSDLDESRID ELCFLGFLGL ADPVRATAAE SVDRLMRAGV RIVMITGDHP STAEAIAVEL
NTLNGGRIMT GPELDELDDE TLTKLLPEVS VFARVTPAHK VRIVSCLRRA GEVVAVTGDG
ANDAPAIRIA NVGIALGSRA TPAARSAADL VVTDDRIETV VDAIVEGRAM WSSVRDALSI
LVGGNLGEII YTIASSLIGA TALNARQLLL VNLLTDLAPA IAVALRPPTS TEPERLLTEG
PEASLGASLM REIYVRAGVT ALAAAMGWLA GRATGTRGRA ATIGLVALVT AQLLQTLSGG
GTNRTVVLAV LASFALLCVI VTAPGVSGFF GCRPLGPVGW TVGLGSAGLA ALIGEVVQRW
LLRPVASAAP RPALTPAPAA A
//
